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Browsing by Author David N. Sheppard
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Showing results 1 to 7 of 7
Issue Date
Title
Author(s)
18-Dec-2020
Carbon monoxide-releasing molecules inhibit the cystic fibrosis transmembrane conductance regulator Cl-channel
Mayuree Rodrat
;
Walailak Jantarajit
;
Demi R.S. Ng
;
Bartholomew S.J. Harvey
;
Jia Liu
;
William J. Wilkinson
;
Narattaphol Charoenphandhu
;
David N. Sheppard
;
College of Biomedical and Life Sciences
;
University of Bristol
;
Mahidol University
;
Academy of Science
1-Mar-2022
Correlating genotype with phenotype using CFTR-mediated whole-cell Cl<sup>−</sup> currents in human nasal epithelial cells
Sabrina Noel
;
Nathalie Servel
;
Aurélie Hatton
;
Anita Golec
;
Mayuree Rodrat
;
Demi R.S. Ng
;
Hongyu Li
;
Iwona Pranke
;
Alexandre Hinzpeter
;
Aleksander Edelman
;
David N. Sheppard
;
Isabelle Sermet-Gaudelus
;
Université Paris Cité
;
Institut Necker-Enfants Malades (INEM)
;
Hôpital Necker Enfants Malades
;
University of Bristol
;
Institute of Molecular Biosciences, Mahidol University
;
European Reference Network for rare respiratory diseases (ERN-LUNG)
1-Jan-2015
Impact of the F508del mutation on ovine CFTR, a Cl<sup>-</sup> channel with enhanced conductance and ATP-dependent gating
Zhiwei Cai
;
Timea Palmai-Pallag
;
Pissared Khuituan
;
Michael J. Mutolo
;
Clément Boinot
;
Beihui Liu
;
Toby S. Scott-Ward
;
Isabelle Callebaut
;
Ann Harris
;
David N. Sheppard
;
University of Bristol
;
Northwestern University Feinberg School of Medicine
;
Mahidol University
;
Universite de Poitiers
;
Sorbonne Universite
;
Weatherall Institute of Molecular Medicine
1-Jan-2014
Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics
Min Ju
;
Toby S. Scott-Ward
;
Jia Liu
;
Pissared Khuituan
;
Hongyu Li
;
Zhiwei Cai
;
Stephen M. Husbands
;
David N. Sheppard
;
University of Bristol
;
Mahidol University
;
University of Bath
1-Jan-2020
Parathyroid hormone increases CFTR expression and function in Caco-2 intestinal epithelial cells
Walailak Jantarajit
;
Kannikar Wongdee
;
Kornkamon Lertsuwan
;
Jarinthorn Teerapornpuntakit
;
Ratchaneevan Aeimlapa
;
Jirawan Thongbunchoo
;
Bartholomew S.J. Harvey
;
David N. Sheppard
;
Narattaphol Charoenphandhu
;
Naresuan University
;
University of Bristol
;
Mahidol University
;
Burapha University
;
Academy of Science
1-Apr-2018
Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small molecule
Jia Liu
;
Hermann Bihler
;
Carlos M. Farinha
;
Nikhil T. Awatade
;
Ana M. Romão
;
Dayna Mercadante
;
Yi Cheng
;
Isaac Musisi
;
Walailak Jantarajit
;
Yiting Wang
;
Zhiwei Cai
;
Margarida D. Amaral
;
Martin Mense
;
David N. Sheppard
;
University of Bristol
;
Mahidol University
;
Faculdade de Ciências, Universidade de Lisboa
;
Cystic Fibrosis Foundation Therapeutics
1-Apr-2022
A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR
Jia Liu
;
Allison P. Berg
;
Yiting Wang
;
Walailak Jantarajit
;
Katy J. Sutcliffe
;
Edward B. Stevens
;
Lishuang Cao
;
Marko J. Pregel
;
David N. Sheppard
;
Pfizer Limited, UK
;
University of Bristol
;
Mahidol University
;
Pfizer Inc.