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Browsing by Author Geoffrey Schwertz

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Showing results 1 to 4 of 4
Issue DateTitleAuthor(s)
22-Jun-2017Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal StructuresGeoffrey Schwertz; Matthias C. Witschel; Matthias Rottmann; Roger Bonnert; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Susan A. Charman; Karen L. White; Abhijit Kundu; Surajit Sadhukhan; Mel Lloyd; Gail M. Freiberg; Myron Srikumaran; Marc Siggel; Adrian Zwyssig; Pimchai Chaiyen; François Diederich; ETH Zurich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Medicines for Malaria Venture; Thailand National Center for Genetic Engineering and Biotechnology; Monash University; TCG Lifesciences Ltd.; Covance Inc.; AbbVie; Mahidol University
12-Oct-2017Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone MotifsGeoffrey Schwertz; Michelle S. Frei; Matthias C. Witschel; Matthias Rottmann; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Nils Trapp; Kerstin Mark; Pimchai Chaiyen; François Diederich; ETH Zurich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; Vidyasirimedhi Institute of Science and Technology
9-Apr-2015Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): Cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activitiesMatthias C. Witschel; Matthias Rottmann; Anatol Schwab; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Michael Seet; Sandro Tonazzi; Geoffrey Schwertz; Frank Stelzer; Thomas Mietzner; Case McNamara; Frank Thater; Céline Freymond; Aritsara Jaruwat; Chatchadaporn Pinthong; Pinpunya Riangrungroj; Mouhssin Oufir; Matthias Hamburger; Pascal Mäser; Laura M. Sanz-Alonso; Susan Charman; Sergio Wittlin; Yongyuth Yuthavong; Pimchai Chaiyen; François Diederich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; ETH Zurich; Thailand National Center for Genetic Engineering and Biotechnology; California Institute for Biomedical Research; Mahidol University; GlaxoSmithKline plc, Spain; Monash Institute of Pharmaceutical Sciences
8-May-2018Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic ScaffoldGeoffrey Schwertz; Matthias C. Witschel; Matthias Rottmann; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Watcharee Amornwatcharapong; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Nils Trapp; Pimchai Chaiyen; François Diederich; Vidyasirimedhi Institute of Science and Technology; ETH Zürich; Universitat Basel; Swiss Tropical and Public Health Institute (Swiss TPH); Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology; BASF SE