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Browsing by Author James A. Watson

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Showing results 1 to 17 of 17
Issue DateTitleAuthor(s)
1-Nov-2020A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in MyanmarJames A. Watson; Thomas Lamb; Jane Holmes; David A. Warrell; Khin Thida Thwin; Zaw Lynn Aung; Min Zaw Oo; Myat Thet Nwe; Frank Smithuis; Elizabeth A. Ashley; Mahosot Hospital, Lao; Mahidol University; Nuffield Department of Medicine; Myanmar Oxford Clinical Research Unit; University of Medicine 1; University of Medicine 2
9-Oct-2020A cautionary note on the use of unsupervised machine learning algorithms to characterise malaria parasite population structure from genetic distance matricesJames A. Watson; Aimee R. Taylor; Elizabeth A. Ashley; Arjen Dondorp; Caroline O. Buckee; Nicholas J. White; Chris C. Holmes; Harvard T.H. Chan School of Public Health; University of Oxford; Mahosot Hospital, Lao; Mahidol University; Nuffield Department of Medicine; Broad Institute
28-Jan-2019Collider bias and the apparent protective effect of glucose-6-phosphate dehydrogenase deficiency on cerebral malariaJames A. Watson; Stije J. Leopold; Julie A. Simpson; Nicholas Pj Day; Arjen M. Dondorp; Nicholas J. White; Melbourne School of Population and Global Health; Mahidol University; Nuffield Department of Clinical Medicine
8-Jul-2020Concentration-dependent mortality of chloroquine in overdoseJames A. Watson; Joel Tarning; Richard M. Hoglund; Frederic J. Baud; Bruno Megarbane; Jean Luc Clemessy; Nicholas J. White; Universite Paris-Saclay; AP-HP Assistance Publique - Hopitaux de Paris; Hôpital Lariboisiere AP-HP; Mahidol University; Nuffield Department of Medicine; Clinique du Sport
3-Dec-2020Concomitant Bacteremia in Adults With Severe Falciparum MalariaNguyen Hoan Phu; Nicholas P.J. Day; Phung Quoc Tuan; Nguyen Thi Hoang Mai; Tran Thi Hong Chau; Ly Van Chuong; Ha Vinh; Pham Phu Loc; Dinh Xuan Sinh; Nguyen Thi Tuyet Hoa; Deborah J. Waller; John Wain; Atthanee Jeyapant; James A. Watson; Jeremy J. Farrar; Tran Tinh Hien; Christopher M. Parry; Nicholas J. White; Oxford University Clinical Research Unit; Hospital for Tropical Diseases Vietnam; Liverpool School of Tropical Medicine; University of Liverpool; Quadram Institute Bioscience; Mahidol University; Nagasaki University; Nuffield Department of Medicine
1-Dec-2020Correction to: Graphing and reporting heterogeneous treatment effects through reference classes (Trials, (2020), 21, 1, (386), 10.1186/s13063-020-04306-1)James A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Medicine
1-Sep-2020COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacologyNicholas J. White; James A. Watson; Richard M. Hoglund; Xin Hui S. Chan; Phaik Yeong Cheah; Joel Tarning; Hospital for Tropical Diseases; Mahidol University; Nuffield Department of Medicine
1-Nov-2019A decision-theoretic approach to the evaluation of machine learning algorithms in computational drug discoveryOliver P. Watson; Isidro Cortes-Ciriano; Aimee R. Taylor; James A. Watson; University of Cambridge; Boston University School of Public Health; Mahidol University; Nuffield Department of Clinical Medicine; Broad Institute; Evariste Technologies Ltd.
19-Nov-2020Effect of hydroxychloroquine in hospitalized patients with Covid-19Peter Horby; Marion Mafham; Louise Linsell; Jennifer L. Bell; Natalie Staplin; Jonathan R. Emberson; Martin Wiselka; Andrew Ustianowski; Einas Elmahi; Benjamin Prudon; Tony Whitehouse; Timothy Felton; John Williams; Jakki Faccenda; Jonathan Underwood; J. Kenneth Baillie; Lucy C. Chappell; Saul N. Faust; Thomas Jaki; Katie Jeffery; Wei Shen Lim; Alan Montgomery; Kathryn Rowan; Joel Tarning; James A. Watson; Nicholas J. White; Edmund Juszczak; Richard Haynes; Martin J. Landray; National Institute for Health Research; North West Anglia NHS Foundation Trust; Cardiff & Vale University Health Board; Manchester University NHS Foundation Trust; Department of Mathematics and Statistics, Lancaster University; University of Cambridge; The James Cook University Hospital; University Hospitals of Leicester NHS Trust; University of Oxford; University Hospitals Birmingham NHS Foundation Trust; University of Edinburgh, Roslin Institute; Nottingham University Hospitals NHS Trust; Northampton General Hospital; North Tees and Hartlepool NHS Foundation Trust; Medical Research Council; University of Nottingham; Mahidol University; King's College London; Nuffield Department of Medicine; North Manchester General Hospital; The University of Manchester; University of Oxford Medical Sciences Division; University Hospital Southampton NHS Foundation Trust; Intensive Care National Audit and Research Centre
7-May-2020Graphing and reporting heterogeneous treatment effects through reference classesJames A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Clinical Medicine
1-Jan-2019Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studiesStije J. Leopold; James A. Watson; Atthanee Jeeyapant; Julie A. Simpson; Nguyen H. Phu; Tran T. Hien; Nicholas P.J. Day; Arjen M. Dondorp; Nicholas J. White; Melbourne School of Population and Global Health; Mahidol University; Nuffield Department of Clinical Medicine; Oxford University Clinical Research Unit
10-Feb-2020Machine learning analysis plans for randomised controlled trials: Detecting treatment effect heterogeneity with strict control of type i errorJames A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Clinical Medicine
1-Jul-2020Non-adherence in non-inferiority trials: Pitfalls and recommendationsYin Mo; Cherry Lim; James A. Watson; Nicholas J. White; Ben S. Cooper; National University Hospital, Singapore; National University of Singapore; Mahidol University; Nuffield Department of Medicine
1-Apr-2019Pharmacokinetic-pharmacodynamic assessment of the hepatic and bone marrow toxicities of the new trypanoside fexinidazoleJames A. Watson; Nathalie Strub-Wourgraft; Antoine Tarral; Isabela Ribeiro; Joel Tarning; Nicholas J. White; Mahidol University; Nuffield Department of Clinical Medicine; Drugs for Neglected Diseases Initiative
1-Feb-2021Protective effect of mediterranean-type glucose-6-phosphate dehydrogenase deficiency against plasmodium vivax malariaGhulam R. Awab; Fahima Aaram; Natsuda Jamornthanyawat; Kanokon Suwannasin; Watcharee Pagornrat; James A. Watson; Charles J. Woodrow; Arjen M. Dondorp; Nicholas P.J. Day; Mallika Imwong; Nicholas J. White; Mahidol University; Nuffield Department of Medicine; Nangarhar University; Kabul Medical University
1-Dec-2019Resolving the cause of recurrent Plasmodium vivax malaria probabilisticallyAimee R. Taylor; James A. Watson; Cindy S. Chu; Kanokpich Puaprasert; Jureeporn Duanguppama; Nicholas P.J. Day; Francois Nosten; Daniel E. Neafsey; Caroline O. Buckee; Mallika Imwong; Nicholas J. White; Shoklo Malaria Research Unit; Harvard T.H. Chan School of Public Health; Mahidol University; Nuffield Department of Clinical Medicine; Broad Institute
1-Jan-2021Time-to-death is a potential confounder in observational studies of blood transfusion in severe malariaJames A. Watson; Stije J. Leopold; Arjen M. Dondorp; Nicholas J. White; Mahidol University; Nuffield Department of Medicine