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Browsing by Author James A. Watson

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Issue DateTitleAuthor(s)
1-Nov-2020A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in MyanmarJames A. Watson; Thomas Lamb; Jane Holmes; David A. Warrell; Khin Thida Thwin; Zaw Lynn Aung; Min Zaw Oo; Myat Thet Nwe; Frank Smithuis; Elizabeth A. Ashley; Mahosot Hospital, Lao; Mahidol University; Nuffield Department of Medicine; Myanmar Oxford Clinical Research Unit; University of Medicine 1; University of Medicine 2
9-Oct-2020A cautionary note on the use of unsupervised machine learning algorithms to characterise malaria parasite population structure from genetic distance matricesJames A. Watson; Aimee R. Taylor; Elizabeth A. Ashley; Arjen Dondorp; Caroline O. Buckee; Nicholas J. White; Chris C. Holmes; Harvard T.H. Chan School of Public Health; University of Oxford; Mahosot Hospital, Lao; Mahidol University; Nuffield Department of Medicine; Broad Institute
1-Jul-2022Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric StudiesJames A. Watson; Stephen M. Kissler; Nicholas P.J. Day; Yonatan H. Grad; Nicholas J. White; Faculty of Tropical Medicine, Mahidol University; Harvard T.H. Chan School of Public Health; Nuffield Department of Medicine
1-Jan-2021Chloroquine/ hydroxychloroquine prevention of coronavirus disease (COVID-19) in the healthcare setting; protocol for a placebo-controlled prophylaxis study (COPCOV)William Hk Schilling; James J. Callery; Walter Taylor; Mavuto Mukaka; Maneerat Ekkapongpisit; James A. Watson; Arjun Chandna; Salwaluk Panapipat; Jaruwan Tubprasert; Prayoon Yuentrakul; Naomi Waithira; Tanya Cope; Mehul Dhorda; Cintia Cruz; Lorenz von Seidlein; Joanne Milton; Martin LLewelyn; Amanda Adler; Kesinee Chotivanich; Phaik Yeong Cheah; Elizabeth A. Ashley; Mayfong Mayxay; Arjen M. Dondorp; Weerapong Phumratanaprapin; Nicholas PJ Day; Nicholas White; Faculty of Tropical Medicine, Mahidol University; Brighton and Sussex Medical School; Mahosot Hospital, Lao; Nuffield Department of Medicine; Cambodia Oxford Medical Research Unit; Diabetes Unit
28-Jan-2019Collider bias and the apparent protective effect of glucose-6-phosphate dehydrogenase deficiency on cerebral malariaJames A. Watson; Stije J. Leopold; Julie A. Simpson; Nicholas Pj Day; Arjen M. Dondorp; Nicholas J. White; Melbourne School of Population and Global Health; Mahidol University; Nuffield Department of Clinical Medicine
8-Jul-2020Concentration-dependent mortality of chloroquine in overdoseJames A. Watson; Joel Tarning; Richard M. Hoglund; Frederic J. Baud; Bruno Megarbane; Jean Luc Clemessy; Nicholas J. White; Universite Paris-Saclay; AP-HP Assistance Publique - Hopitaux de Paris; Hôpital Lariboisiere AP-HP; Mahidol University; Nuffield Department of Medicine; Clinique du Sport
3-Dec-2020Concomitant Bacteremia in Adults With Severe Falciparum MalariaNguyen Hoan Phu; Nicholas P.J. Day; Phung Quoc Tuan; Nguyen Thi Hoang Mai; Tran Thi Hong Chau; Ly Van Chuong; Ha Vinh; Pham Phu Loc; Dinh Xuan Sinh; Nguyen Thi Tuyet Hoa; Deborah J. Waller; John Wain; Atthanee Jeyapant; James A. Watson; Jeremy J. Farrar; Tran Tinh Hien; Christopher M. Parry; Nicholas J. White; Oxford University Clinical Research Unit; Hospital for Tropical Diseases Vietnam; Liverpool School of Tropical Medicine; University of Liverpool; Quadram Institute Bioscience; Mahidol University; Nagasaki University; Nuffield Department of Medicine
1-Dec-2020Correction to: Graphing and reporting heterogeneous treatment effects through reference classes (Trials, (2020), 21, 1, (386), 10.1186/s13063-020-04306-1)James A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Medicine
1-Sep-2020COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacologyNicholas J. White; James A. Watson; Richard M. Hoglund; Xin Hui S. Chan; Phaik Yeong Cheah; Joel Tarning; Hospital for Tropical Diseases; Mahidol University; Nuffield Department of Medicine
1-Nov-2019A decision-theoretic approach to the evaluation of machine learning algorithms in computational drug discoveryOliver P. Watson; Isidro Cortes-Ciriano; Aimee R. Taylor; James A. Watson; University of Cambridge; Boston University School of Public Health; Mahidol University; Nuffield Department of Clinical Medicine; Broad Institute; Evariste Technologies Ltd.
1-Nov-2021Determinants of primaquine and carboxyprimaquine exposures in children and adults with plasmodium vivax malariaCindy S. Chu; James A. Watson; Aung Pyae Phyo; Htun Htun Win; Widi Yotyingaphiram; Suradet Thinraow; Nay Lin Soe; Aye Aye Aung; Pornpimon Wilaisrisak; Kanokpich Kraft; Mallika Imwong; Warunee Hanpithakpong; Daniel Blessborn; Joel Tarning; Stéphane Proux; Clare Ling; François H. Nosten; Nicholas J. White; Faculty of Tropical Medicine, Mahidol University; Nuffield Department of Medicine
19-Nov-2020Effect of hydroxychloroquine in hospitalized patients with Covid-19Peter Horby; Marion Mafham; Louise Linsell; Jennifer L. Bell; Natalie Staplin; Jonathan R. Emberson; Martin Wiselka; Andrew Ustianowski; Einas Elmahi; Benjamin Prudon; Tony Whitehouse; Timothy Felton; John Williams; Jakki Faccenda; Jonathan Underwood; J. Kenneth Baillie; Lucy C. Chappell; Saul N. Faust; Thomas Jaki; Katie Jeffery; Wei Shen Lim; Alan Montgomery; Kathryn Rowan; Joel Tarning; James A. Watson; Nicholas J. White; Edmund Juszczak; Richard Haynes; Martin J. Landray; National Institute for Health Research; North West Anglia NHS Foundation Trust; Cardiff & Vale University Health Board; Manchester University NHS Foundation Trust; Department of Mathematics and Statistics, Lancaster University; University of Cambridge; The James Cook University Hospital; University Hospitals of Leicester NHS Trust; University of Oxford; University Hospitals Birmingham NHS Foundation Trust; University of Edinburgh, Roslin Institute; Nottingham University Hospitals NHS Trust; Northampton General Hospital; North Tees and Hartlepool NHS Foundation Trust; Medical Research Council; University of Nottingham; Mahidol University; King's College London; Nuffield Department of Medicine; North Manchester General Hospital; The University of Manchester; University of Oxford Medical Sciences Division; University Hospital Southampton NHS Foundation Trust; Intensive Care National Audit and Research Centre
1-Jan-2022Falciparum malaria mortality in sub-Saharan Africa in the pretreatment eraJames A. Watson; Nicholas J. White; Arjen M. Dondorp; Faculty of Tropical Medicine, Mahidol University; Nuffield Department of Medicine
7-May-2020Graphing and reporting heterogeneous treatment effects through reference classesJames A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Clinical Medicine
1-Jan-2021Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precisionJames A. Watson; Carolyne M. Ndila; Sophie Uyoga; Alexander Macharia; Gideon Nyutu; Shebe Mohammed; Caroline Ngetsa; Neema Mturi; Norbert Peshu; Benjamin Tsofa; Kirk Rockett; Stije Leopold; Hugh Kingston; Elizabeth C. George; Kathryn Maitland; Nicholas P.J. Day; Arjen M. Dondorp; Philip Bejon; Thomas Williams; Chris C. Holmes; Nicholas J. White; Faculty of Tropical Medicine, Mahidol University; The Wellcome Centre for Human Genetics; Centre for Geographic Medicine Research; University of Oxford; University College London; Imperial College London; Nuffield Department of Medicine; Wellcome Sanger Institute
20-Jul-2022Improving the diagnosis of severe malaria in African children using platelet counts and plasma PfHRP2 concentrationsJames A. Watson; Sophie Uyoga; Perpetual Wanjiku; Johnstone Makale; Gideon M. Nyutu; Neema Mturi; Elizabeth C. George; Charles J. Woodrow; Nicholas P.J. Day; Philip Bejon; Robert O. Opoka; Arjen M. Dondorp; Chandy C. John; Kathryn Maitland; Thomas N. Williams; Nicholas J. White; Faculty of Tropical Medicine, Mahidol University; Makerere University; Wellcome Trust Research Laboratories Nairobi; University College London; Imperial College London; Nuffield Department of Medicine; Indiana University
1-Jan-2019Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studiesStije J. Leopold; James A. Watson; Atthanee Jeeyapant; Julie A. Simpson; Nguyen H. Phu; Tran T. Hien; Nicholas P.J. Day; Arjen M. Dondorp; Nicholas J. White; Melbourne School of Population and Global Health; Mahidol University; Nuffield Department of Clinical Medicine; Oxford University Clinical Research Unit
10-Feb-2020Machine learning analysis plans for randomised controlled trials: Detecting treatment effect heterogeneity with strict control of type i errorJames A. Watson; Chris C. Holmes; University of Oxford; Mahidol University; Nuffield Department of Clinical Medicine
1-Jun-2022Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarialsNicholas J. White; James A. Watson; J. Kevin Baird; Faculty of Tropical Medicine, Mahidol University; Eijkman Institute for Molecular Biology; Nuffield Department of Medicine
1-Jul-2020Non-adherence in non-inferiority trials: Pitfalls and recommendationsYin Mo; Cherry Lim; James A. Watson; Nicholas J. White; Ben S. Cooper; National University Hospital, Singapore; National University of Singapore; Mahidol University; Nuffield Department of Medicine