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Browsing by Author Penchit Chitnumsub

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Showing results 1 to 19 of 19

Issue Date	Title	Author(s)
22-Jun-2017	Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures	Geoffrey Schwertz; Matthias C. Witschel; Matthias Rottmann; Roger Bonnert; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Susan A. Charman; Karen L. White; Abhijit Kundu; Surajit Sadhukhan; Mel Lloyd; Gail M. Freiberg; Myron Srikumaran; Marc Siggel; Adrian Zwyssig; Pimchai Chaiyen; François Diederich; ETH Zurich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Medicines for Malaria Venture; Thailand National Center for Genetic Engineering and Biotechnology; Monash University; TCG Lifesciences Ltd.; Covance Inc.; AbbVie; Mahidol University
1-Apr-2004	Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum	Penchit Chitnumsub; Jirundon Yavaniyama; Jarunee Vanichtanankul; Sumalee Kamchonwongpaisan; Malcolm D. Walkinshaw; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; University of Edinburgh
12-Oct-2017	Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs	Geoffrey Schwertz; Michelle S. Frei; Matthias C. Witschel; Matthias Rottmann; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Nils Trapp; Kerstin Mark; Pimchai Chaiyen; François Diederich; ETH Zurich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; Vidyasirimedhi Institute of Science and Technology
13-Sep-2005	Crystal structure of dihydrofolate reductase from Plasmodium vivax: Pyrimethamine displacement linked with mutation-induced resistance	Palangpon Kongsaeree; Puttapol Khongsuk; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Bongkoch Tarnchompoo; Malcolm D. Walkinshaw; Yongyuth Yuthavong; Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology; University of Edinburgh
1-Dec-2009	Crystallization and preliminary crystallographic studies of dihydrofolate reductase-thymidylate synthase from Trypanosoma cruzi, the Chagas disease pathogen	Penchit Chitnumsub; Jirundon Yuvaniyama; Thippayarat Chahomchuen; Tirayut Vilaivan; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; Chulalongkorn University
1-Jun-2004	Erratum: Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum (Acta Crystallographica Section D: Biological Crystallography (2004) D60 (780-783))	Penchit Chitnumsub; Jirundon Yuvaniyama; Jarunee Vanichtanankul; Sumalee Kamchonwongpaisan; Malcolm D. Walkinshaw; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; University of Edinburgh
15-Sep-2017	Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior	Watcharee Amornwatcharapong; Somchart Maenpuen; Penchit Chitnumsub; Ubolsree Leartsakulpanich; Pimchai Chaiyen; Mahidol University; Burapha University; Thailand National Center for Genetic Engineering and Biotechnology; Vidyasirimedhi Institute of Science and Technology
9-Apr-2015	Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): Cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities	Matthias C. Witschel; Matthias Rottmann; Anatol Schwab; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Michael Seet; Sandro Tonazzi; Geoffrey Schwertz; Frank Stelzer; Thomas Mietzner; Case McNamara; Frank Thater; Céline Freymond; Aritsara Jaruwat; Chatchadaporn Pinthong; Pinpunya Riangrungroj; Mouhssin Oufir; Matthias Hamburger; Pascal Mäser; Laura M. Sanz-Alonso; Susan Charman; Sergio Wittlin; Yongyuth Yuthavong; Pimchai Chaiyen; François Diederich; BASF SE; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; ETH Zurich; Thailand National Center for Genetic Engineering and Biotechnology; California Institute for Biomedical Research; Mahidol University; GlaxoSmithKline plc, Spain; Monash Institute of Pharmaceutical Sciences
1-May-2003	Insights into antifolate resistance from malarial DHFR-TS structures	Jirundon Yuvaniyama; Penchit Chitnumsub; Sumalee Kamchonwongpaisan; Jarunee Vanichtanankul; Worachart Sirawaraporn; Paul Taylor; Malcolm D. Walkinshaw; Yongyuth Yuthavong; Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology; University of Edinburgh
27-Mar-2015	Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase	Somchart Maenpuen; Watcharee Amornwatcharapong; Pasupat Krasatong; Jeerus Sucharitakul; Bruce A. Palfey; Yongyuth Yuthavong; Penchit Chitnumsub; Ubolsree Leartsakulpanich; Pimchai Chaiyen; Mahidol University; Burapha University; Chulalongkorn University; University of Michigan, Ann Arbor; Thailand National Center for Genetic Engineering and Biotechnology
16-Oct-2012	Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target	Yongyuth Yuthavong; Bongkoch Tarnchompoo; Tirayut Vilaivan; Penchit Chitnumsub; Sumalee Kamchonwongpaisan; Susan A. Charman; Danielle N. McLennan; Karen L. White; Livia Vivas; Emily Bongard; Chawanee Thongphanchang; Supannee Taweechai; Jarunee Vanichtanankul; Roonglawan Rattanajak; Uthai Arwon; Pascal Fantauzzi; Jirundon Yuvaniyama; William N. Charman; David Matthews; Thailand National Center for Genetic Engineering and Biotechnology; Chulalongkorn University; Monash University; London School of Hygiene & Tropical Medicine; Medicines for Malaria Venture; Mahidol University
8-May-2018	Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold	Geoffrey Schwertz; Matthias C. Witschel; Matthias Rottmann; Ubolsree Leartsakulpanich; Penchit Chitnumsub; Aritsara Jaruwat; Watcharee Amornwatcharapong; Wanwipa Ittarat; Anja Schäfer; Raphael A. Aponte; Nils Trapp; Pimchai Chaiyen; François Diederich; Vidyasirimedhi Institute of Science and Technology; ETH Zürich; Universitat Basel; Swiss Tropical and Public Health Institute (Swiss TPH); Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology; BASF SE
21-Mar-2003	Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites	Alireza Sardarian; Kenneth T. Douglas; Martin Read; Paul F G Sims; John E. Hyde; Penchit Chitnumsub; Rachada Sirawaraporn; Worachart Sirawaraporn; University of Manchester; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University
1-Dec-2000	Pyrimethamine analogue inhibitors of resistance mutants of Plasmodial dihydrofolate reductase	Ali Sardarian; Kenneth T. Douglas; Penchit Chitnumsub; Worachart Sirawaraporn; University of Manchester; Thailand National Science and Technology Development Agency; Mahidol University
1-Jan-2014	The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities	Penchit Chitnumsub; Wanwipa Ittarat; Aritsara Jaruwat; Krittikar Noytanom; Watcharee Amornwatcharapong; Wichai Pornthanakasem; Pimchai Chaiyen; Yongyuth Yuthavong; Ubolsree Leartsakulpanich; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University
1-Jan-2014	Structures of Plasmodium vivax serine hydroxymethyltransferase: Implications for ligand-binding specificity and functional control	Penchit Chitnumsub; Aritsara Jaruwat; Pinpunya Riangrungroj; Wanwipa Ittarat; Krittikar Noytanom; Worrapoj Oonanant; Jarunee Vanichthanankul; Phimonphan Chuankhayan; Somchart Maenpuen; Chun Jung Chen; Pimchai Chaiyen; Yongyuth Yuthavong; Ubolsree Leartsakulpanich; Thailand National Center for Genetic Engineering and Biotechnology; National Synchrotron Radiation Research Center Taiwan; Burapha University; Mahidol University
1-Jan-2005	Subunit complementation of thymidylate synthase in Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase	Manee Chanama; Penchit Chitnumsub; Yongyuth Yuthavong; Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology
14-Jan-2000	Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs	Rongbao Li; Rachada Sirawaraporn; Penchit Chitnumsub; Worachart Sirawaraporn; Jason Wooden; Francis Athappilly; Stewart Turley; Wim G.J. Hol; University of Washington, Seattle; Mahidol University; Thailand National Science and Technology Development Agency
2-Sep-2011	Trypanosomal dihydrofolate reductase reveals natural antifolate resistance	Jarunee Vanichtanankul; Supannee Taweechai; Jirundon Yuvaniyama; Tirayut Vilaivan; Penchit Chitnumsub; Sumalee Kamchonwongpaisan; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University; Chulalongkorn University

Showing results 1 to 19 of 19