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Browsing by Author Thierry T. Diagana

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Showing results 1 to 9 of 9
Issue DateTitleAuthor(s)
22-Sep-2016Antimalarial activity of KAF156 in falciparum and vivax malariaNicholas J. White; Tran T. Duong; Chirapong Uthaisin; Fran'ois Nosten; Aung P. Phyo; Borimas Hanboonkunupakarn; Sasithon Pukrittayakamee; Podjanee Jittamala; Kittiphum Chuthasmit; Ming S. Cheung; Yiyan Feng; Ruobing Li; Baldur Magnusson; Marc Sultan; Daniela Wieser; Xiaolei Xun; Rong Zhao; Thierry T. Diagana; Peter Pertel; F. Joel Leong; Mahidol-Oxford Tropical Medicine Research Unit; Department of Clinical Tropical Medicine; Mahidol University; Phusing Hospital; Mae Ramat District Hospital; Nuffield Department of Clinical Medicine; National Institute of Malaria, Parasitology and Entomology; Novartis International AG; Novartis Institutes for BioMedical Research; Novartis Institutes for Biomedical Research; Novartis Institute for Tropical Diseases Pte. Ltd.; Novartis Institutes for BioMedical Research, Inc.
1-Sep-2019Hepatic spheroids used as an in vitro model to study malaria relapseAdeline C.Y. Chua; Abhishek Ananthanarayanan; Jessica Jie Ying Ong; Jen Yi Wong; Andy Yip; Nisha Hari Singh; Yinghua Qu; Laurent Dembele; Michael McMillian; Ratawan Ubalee; Silas Davidson; Anchalee Tungtaeng; Rawiwan Imerbsin; Kapish Gupta; Chiara Andolina; Fan Lee; Kevin S-W Tan; François Nosten; Bruce Russell; Amber Lange; Thierry T. Diagana; Laurent Rénia; Bryan K.S. Yeung; Hanry Yu; Pablo Bifani; A-Star, Singapore Immunology Network; Mechanobiology Institute, Singapore; Yong Loo Lin School of Medicine; A-Star, Institute of Bioengineering and Nanotechnology; Novartis Institute for Tropical Diseases Pte. Ltd.; University of Otago; Armed Forces Research Institute of Medical Sciences, Thailand; Mahidol University; Nuffield Department of Clinical Medicine; Novartis Institutes for BioMedical Research, Inc.; Invitrocue Pte Ltd. 138667; Université des Sciences
1-May-2018Imidazolopiperazines kill both rings and dormant rings in wild-type and K13 artemisinin-resistant plasmodium falciparum In VitroLaurent Dembele; Devendra Kumar Gupta; Michelle Yi Xiu Lim; Xiaoman Ang; Jeremy J. Selva; Kesinee Chotivanich; Chea Nguon; Arjen M. Dondorp; Ghislain M.C. Bonamy; Thierry T. Diagana; Pablo Bifania; A-Star, Singapore Immunology Network; Yong Loo Lin School of Medicine; Novartis Institute for Tropical Diseases Pte. Ltd.; Mahidol University; Nuffield Department of Clinical Medicine; Amsterdam UMC - University of Amsterdam; Université des Sciences; National Center for Parasitology, Entomology and Malaria Control
1-Jan-2014KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmissionKelli L. Kuhen; Arnab K. Chatterjee; Matthias Rottmann; Kerstin Gagaring; Rachel Borboa; Jennifer Buenviaje; Zhong Chen; Carolyn Francek; Tao Wu; Advait Nagle; S. Whitney Barnes; David Plouffe; Marcus C.S. Lee; David A. Fidock; Wouter Graumans; Marga Van De Vegte-Bolmer; Geert J. Van Gemert; Grennady Wirjanata; Boni Sebayang; Jutta Marfurt; Bruce Russell; Rossarin Suwanarusk; Ric N. Price; Francois Nosten; Anchalee Tungtaeng; Montip Gettayacamin; Jetsumon Sattabongkot; Jennifer Taylor; John R. Walker; David Tully; Kailash P. Patra; Erika L. Flannery; Joseph M. Vinetz; Laurent Renia; Robert W. Sauerwein; Elizabeth A. Winzeler; Richard J. Glynne; Thierry T. Diagana; The Genomics Institute of the Novartis Research Foundation; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Columbia University, College of Physicians and Surgeons; Radboud University Nijmegen Medical Centre; Menzies School of Health Research; Eijkman Institute for Molecular Biology; Agency for Science, Technology and Research, Singapore; Shoklo Malaria Research Unit; Mahidol University; Nuffield Department of Clinical Medicine; Armed Forces Research Institute of Medical Sciences, Thailand; University of California, San Diego; University of California, San Diego, School of Medicine; Novartis Institute for Tropical Diseases Pte. Ltd.; California Institute for Biomedical Research
1-Dec-2019Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stagesAdeline C.Y. Chua; Jessica Jie Ying Ong; Benoit Malleret; Rossarin Suwanarusk; Varakorn Kosaisavee; Anne Marie Zeeman; Caitlin A. Cooper; Kevin S.W. Tan; Rou Zhang; Bee Huat Tan; Siti Nurdiana Abas; Andy Yip; Anne Elliot; Chester J. Joyner; Jee Sun Cho; Kate Breyer; Szczepan Baran; Amber Lange; Steven P. Maher; François Nosten; Christophe Bodenreider; Bryan K.S. Yeung; Dominique Mazier; Mary R. Galinski; Nathalie Dereuddre-Bosquet; Roger Le Grand; Clemens H.M. Kocken; Laurent Rénia; Dennis E. Kyle; Thierry T. Diagana; Georges Snounou; Bruce Russell; Pablo Bifani; A-Star, Singapore Immunology Network; Centre de Recherche en Immunologie des Infections Virales et des Maladies Auto-Immunes; London School of Hygiene & Tropical Medicine; The University of Georgia; Yong Loo Lin School of Medicine; Novartis Institute for Tropical Diseases Pte. Ltd.; Biomedical Primate Research Centre - Rijswijk; University of Otago; Mahidol University; Nuffield Department of Clinical Medicine; Sorbonne Universite; Emory University; Inserm; Novartis Institutes for BioMedical Research
1-Jan-2014Spiroindolone KAE609 for falciparum and vivax malariaNicholas J. White; Sasithon Pukrittayakamee; Aung Pyae Phyo; Ronnatrai Rueangweerayut; François Nosten; Podjanee Jittamala; Atthanee Jeeyapant; Jay Prakash Jain; Gilbert Lefèvre; Ruobing Li; Baldur Magnusson; Thierry T. Diagana; F. Joel Leong; Mahidol University; Mae Sot General Hospital; Nuffield Department of Clinical Medicine; Novartis Healthcare Pvt. Ltd.; Novartis International AG; Institute of Biomedical Science; Novartis Institute for Tropical Diseases Pte. Ltd.
3-Sep-2010Spiroindolones, a potent compound class for the treatment of malariaMatthias Rottmann; Case McNamara; Bryan K.S. Yeung; Marcus C.S. Lee; Bin Zou; Bruce Russell; Patrick Seitz; David M. Plouffe; Neekesh V. Dharia; Jocelyn Tan; Steven B. Cohen; Kathryn R. Spencer; Gonzalo E. González-Páez; Suresh B. Lakshminarayana; Anne Goh; Rossarin Suwanarusk; Timothy Jegla; Esther K. Schmitt; Hans Peter Beck; Reto Brun; Francois Nosten; Laurent Renia; Veronique Dartois; Thomas H. Keller; David A. Fidock; Elizabeth A. Winzeler; Thierry T. Diagana; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; The Genomics Institute of the Novartis Research Foundation; Novartis Institute for Tropical Diseases Pte. Ltd.; Columbia University Medical Center; Agency for Science, Technology and Research, Singapore; National University of Singapore; Scripps Research Institute; Pennsylvania State University; Novartis International AG; Shoklo Malaria Research Unit; Mahidol University; Nuffield Department of Clinical Medicine
29-Nov-2013Targeting Plasmodium PI(4)K to eliminate malariaCase W. McNamara; Marcus C.S. Lee; Chek Shik Lim; Siau Hoi Lim; Jason Roland; Advait Nagle; Oliver Simon; Bryan K.S. Yeung; Arnab K. Chatterjee; Susan L. McCormack; Micah J. Manary; Anne Marie Zeeman; Koen J. Dechering; T. R.Santha Kumar; Philipp P. Henrich; Kerstin Gagaring; Maureen Ibanez; Nobutaka Kato; Kelli L. Kuhen; Christoph Fischli; Matthias Rottmann; David M. Plouffe; Badry Bursulaya; Stephan Meister; Lucia Rameh; Joerg Trappe; Dorothea Haasen; Martijn Timmerman; Robert W. Sauerwein; Rossarin Suwanarusk; Bruce Russell; Laurent Renia; Francois Nosten; David C. Tully; Clemens H.M. Kocken; Richard J. Glynne; Christophe Bodenreider; David A. Fidock; Thierry T. Diagana; Elizabeth A. Winzeler; The Genomics Institute of the Novartis Research Foundation; Columbia University Medical Center; Novartis Institutes for Tropical Disease; University of California, San Diego; Biomedical Primate Research Centre - Rijswijk; TropIQ Health Sciences; Swiss Tropical and Public Health Institute (Swiss TPH); Universitat Basel; Boston University School of Medicine; Novartis International AG; Radboud University Nijmegen Medical Centre; Agency for Science, Technology and Research, Singapore; Yong Loo Lin School of Medicine; Nuffield Department of Clinical Medicine; Mahidol University
1-Dec-2018Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancyNicole L. Bertschi; Annemarie Voorberg-Van der Wel; Anne Marie Zeeman; Sven Schuierer; Florian Nigsch; Walter Carbone; Judith Knehr; Devendra K. Gupta; Sam O. Hofman; Nicole van der Werff; Ivonne Nieuwenhuis; Els Klooster; Bart W. Faber; Erika L. Flannery; Sebastian A. Mikolajczak; Vorada Chuenchob; Binesh Shrestha; Martin Beibel; Tewis Bouwmeester; Niwat Kangwanrangsan; Jetsumon Sattabongkot; Thierry T. Diagana; Clemens H.M. Kocken; Guglielmo Roma; Biomedical Primate Research Centre - Rijswijk; Mahidol University; Novartis International AG; Novartis Pharmaceuticals