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Browsing by Author Worachart Sirawaraporn

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Issue DateTitleAuthor(s)
1-Jan-2004Analysis in Escherichia coli of Plasmodium falciparum dihydropteroate synthase (DHPS) alleles implicated in resistance to sulfadoxineJanette Berglez; Peter Iliades; Worachart Sirawaraporn; Peter Coloe; Ian Macreadie; Biomolecular Research Institute; RMIT University; Mahidol University
18-Feb-1997Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductaseWorachart Sirawaraporn; Tanajit Sathitkul; Rachada Sirawaraporn; Yongyuth Yuthavong; Daniel V. Santi; Mahidol University; University of California, San Francisco; Thailand National Science and Technology Development Agency
6-Mar-2015Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseasesKevin Williams; Elizabeth Bilsland; Andrew Sparkes; Wayne Aubrey; Michael Young; Larisa N. Soldatova; Kurt De Grave; Jan Ramon; Michaela De Clare; Worachart Sirawaraporn; Stephen G. Oliver; Ross D. King; Aberystwyth University; University of Cambridge; Universidade Estadual de Campinas; Brunel University London; KU Leuven; Mahidol University; University of Manchester
2-Dec-1996Chemical synthesis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase genePhisit Prapunwattana; Worachart Sirawaraporn; Yongyuth Yuthavong; Daniel V. Santi; Mahidol University; University of California, San Francisco; Chulalongkorn University; Thailand National Science and Technology Development Agency
1-Nov-1999Cloning and expression of Mycobacterium tuberculosis and Mycobacterium leprae dihydropteroate synthase in Escherichia coliVanida Nopponpunth; Worachart Sirawaraporn; Patricia J. Greene; Daniel V. Santi; Mahidol University; University of California, San Francisco
6-Oct-2000Crystal structure of Mycobacterium tuberculosis 6-hydroxymethyl-7,8-dihydropteroate synthase in complex with pterin monophosphate: New insight into the enzymatic mechanism and sulfa-drug actionArthur M. Baca; Rachada Sirawaraporn; Stewart Turley; Worachart Sirawaraporn; Wim G.J. Hol; University of Washington, Seattle; Mahidol University
15-Jan-2014Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzymeLegesse Adane; Shweta Bhagat; Minhajul Arfeen; Sonam Bhatia; Rachada Sirawaraporn; Worachart Sirawaraporn; Asit K. Chakraborti; Prasad V. Bharatam; National Institute of Pharmaceutical Education and Research India, Mohali; Mahidol University
14-Mar-2002Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine resistant Plasmodium falciparumBongkoch Tarnchompoo; Chawanee Sirichaiwat; Worrapong Phupong; Chakapong Intaraudom; Worachart Sirawaraporn; Sumalee Kamchonwongpaisan; Jarunee Vanichtanankul; Yodhathai Thebtaranonth; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University
13-Jul-2000Development of a lead inhibitor for the A16V+S108T mutant of dihydrofolate reductase from the cycloguanil-resistant strain (T9/94) of Plasmodium falciparumYongyuth Yuthavong; Tirayut Vilaivan; Netnapa Chareonsethakul; Sumalee Kamchonwongpaisan; Worachart Sirawaraporn; Rachel Quarrell; Gordon Lowe; Thailand National Center for Genetic Engineering and Biotechnology; Chulalongkorn University; Mahidol University; University of Oxford
1-Dec-1998Dihydrofolate reductase and antifolate resistance in malariaWorachart Sirawaraporn; Mahidol University
3-Jul-2003Docking and database screening reveal new classes of Plasmodium falciparum dihydrofolate reductase inhibitorsGiulio Rastelli; Sara Pacchioni; Worachart Sirawaraporn; Rachada Sirawaraporn; Marco Daniele Parenti; Anna Maria Ferrari; Universita degli Studi di Modena e Reggio Emilia; Mahidol University
20-Aug-1998Effect of HIV-specific immune-based therapy in subjects infected with HIV-1 subtype E in ThailandVina Churdboonchart; Ronald B. Moss; Worachart Sirawaraporn; Buranaj Smutharaks; Reungpung Sutthent; Fred C. Jensen; Prawut Vacharak; Janet Grimes; Georgia Theofan; Dennis J. Carlo; Mahidol University; Orchestra Therapeutics Inc; Harvard School of Public Health
1-Sep-2006Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparumKristen M. Massimine; Michael T. McIntosh; Lanxuan T. Doan; Chloé E. Atreya; Stephan Gromer; Worachart Sirawaraporn; David A. Elliott; Keith A. Joiner; R. Heiner Schirmer; Karen S. Anderson; Yale University School of Medicine; Universitat Heidelberg; Mahidol University; University of Arizona Medical Center
1-Jan-2011Factors associated with regional bias of pfcrt (plasmodium falciparum chloroquine resistance transporter) haplotypes in NapalMegha Raj Banjara; Mallika Imwong; Songsak Petmitr; Worachart Sirawaraporn; Anand B. Joshi; Porntip Chavalitshewinkoon-Petmitr; Mahidol University; Tribhuvan University
1-Dec-1990Heterologous Expression of Active Thymidylate Synthase–Dihydrofolate Reductase from Plasmodium falciparumWorachart Sirawaraporn; Rachada Sirawaraporn; Yongyuth Yuthavong; Alan F. Cowman; Daniel V. Santi; Mahidol University; Walter and Eliza Hall Institute of Medical Research; University of California, San Francisco
12-Jun-2004Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparumMichael Alifrangis; Inge T. Christensen; Flemming S. Jørgensen; Anita M. Rønn; Jimmy E. Weng; Ming Chen; Ib C. Bygbjerg; Worachart Sirawaraporn; Yaseelan Palarasah; Claus Koch; Kobenhavns Universitet; Copenhagen University Hospital; University of Copenhagen, Faculty of Pharmaceutical Sciences; Statens Serum Institut; Mahidol University; Novo Nordisk AS
29-Jan-2004Inhibitors of Multiple Mutants of Plasmodium falciparum Dihydrofolate Reductase and Their Antimalarial ActivitiesSumalee Kamchonwongpaisan; Rachel Quarrell; Netnapa Charoensetakul; Rachel Ponsinet; Tirayut Vilaivan; Jarunee Vanichtanankul; Bongkoch Tarnchompoo; Worachart Sirawaraporn; Gordon Lowe; Yongyuth Yuthavong; Thailand National Center for Genetic Engineering and Biotechnology; Chulalongkorn University; Mahidol University; University of Oxford
1-May-2003Insights into antifolate resistance from malarial DHFR-TS structuresJirundon Yuvaniyama; Penchit Chitnumsub; Sumalee Kamchonwongpaisan; Jarunee Vanichtanankul; Worachart Sirawaraporn; Paul Taylor; Malcolm D. Walkinshaw; Yongyuth Yuthavong; Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology; University of Edinburgh
2013Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthaseNatpasit Chaianantakul; Rachada Sirawaraporn; Worachart Sirawaraporn; Mahidol University. Faculty of Science. Department of Biochemistry
15-Mar-2013Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthaseNatpasit Chaianantakul; Rachada Sirawaraporn; Worachart Sirawaraporn; Mahidol University