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dc.contributor.authorJames V. Conlanen_US
dc.contributor.authorRichard G. Jarmanen_US
dc.contributor.authorKhamphouth Vongxayen_US
dc.contributor.authorPiyawan Chinnawirotpisanen_US
dc.contributor.authorMelanie C. Melendrezen_US
dc.contributor.authorStanley Fenwicken_US
dc.contributor.authorR. C.Andrew Thompsonen_US
dc.contributor.authorStuart D. Blacksellen_US
dc.contributor.otherMurdoch Universityen_US
dc.contributor.otherArmed Forces Research Institute of Medical Sciences, Thailanden_US
dc.contributor.otherMinistry of Agriculture and Forestryen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherNuffield Department of Clinical Medicineen_US
dc.date.accessioned2018-05-03T07:56:07Z-
dc.date.available2018-05-03T07:56:07Z-
dc.date.issued2011-08-01en_US
dc.identifier.citationInfection, Genetics and Evolution. Vol.11, No.6 (2011), 1306-1311en_US
dc.identifier.issn15677257en_US
dc.identifier.issn15671348en_US
dc.identifier.other2-s2.0-79960404031en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79960404031&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/11292-
dc.description.abstractThe objective of this study was to determine the prevalence and genotypic range of Hepatitis E virus (HEV) in the pig population of northern Lao People's Democratic Republic (PDR). We collected 181 faecal samples from indigenous-breed pigs ≤6 months of age and the faeces was stored in RNA stabilisation buffer due to cold-chain and transport limitations. Twenty-one (11.6%) pigs had detectable HEV RNA and 43.5% of village pig herds were infected. Based on a 240 base pair-nucleotide sequence flanking the junction of open reading frames 1, 2 and 3 (ORF1, ORF2 and ORF3) the isolates were phylogenetically classified within genotype 4. Phylogenetic analyses revealed distinct genetic groupings of the Lao HEV isolates and two groups clustered with human and pig HEV isolates from China. This was the first study to demonstrate genotype 4 HEV in Lao PDR and indicates pigs are a potential reservoir for human HEV infection. © 2011 Elsevier B.V.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79960404031&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleHepatitis E virus is prevalent in the pig population of Lao People's Democratic Republic and evidence exists for homogeneity with Chinese Genotype 4 human isolatesen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1016/j.meegid.2011.04.022en_US
Appears in Collections:Scopus 2011-2015

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