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dc.contributor.authorKaren Gaudinen_US
dc.contributor.authorTina Kaussen_US
dc.contributor.authorAlexandra Gauberten_US
dc.contributor.authorVincent Viauden_US
dc.contributor.authorJean Pierre Dubosten_US
dc.contributor.authorPiero Olliaroen_US
dc.contributor.authorNicholas J. Whiteen_US
dc.contributor.authorPascal Milleten_US
dc.contributor.otherDeveloppements Analytiques et Pharmaceutiques Appliques aux Maladies Negligees et Aux Contrefaconsen_US
dc.contributor.otherOrganisation Mondiale de la Santeen_US
dc.contributor.otherNuffield Department of Clinical Medicineen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-05-03T07:59:46Z-
dc.date.available2018-05-03T07:59:46Z-
dc.date.issued2011-11-01en_US
dc.identifier.citationAnalytical Letters. Vol.44, No.16 (2011), 2732-2743en_US
dc.identifier.issn1532236Xen_US
dc.identifier.issn00032719en_US
dc.identifier.other2-s2.0-84857770029en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84857770029&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/11448-
dc.description.abstractChromatographic parameter assessments for RP-HPLC-UV method development for the simultaneous analysis of artemether and azithromycin for the pharmaceutical analysis of a rectal coformulation currently under development for the treatment of malaria infected children. Using methanol based mobile phase for the analysis of both artemether and azithromycin provided a more robust method in terms of resolution and peak symmetry. The method validated for suppository used 80% methanol and 20% phosphate buffer 15 mM at pH 9. The UV detection was at 210 nm. The accuracy profiles indicated a method validation between 80-120% for both active pharmaceutical ingredients. The preparation process of the suppository was validated based on theoretical values of artemether and azithromycin present in the formulation; active pharmaceutical ingredients were homogenously distributed within the suppository. © 2011 Copyright Taylor and Francis Group, LLC.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84857770029&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.titleSimultaneous Determination of Artemether and Azithromycin in Suppositories by Reversed Phase HPLCen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1080/00032719.2011.553014en_US
Appears in Collections:Scopus 2011-2015

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