Simple jQuery Dropdowns
Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLalana Kongkaneramiten_US
dc.contributor.authorWasu Witoonsaridsilpen_US
dc.contributor.authorPenchom Peungvichaen_US
dc.contributor.authorKornkanok Ingkaninanen_US
dc.contributor.authorNeti Waranuchen_US
dc.contributor.authorNarong Sarisutaen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherNaresuan Universityen_US
dc.identifier.citationExperimental and Therapeutic Medicine. Vol.2, No.1 (2011), 143-148en_US
dc.description.abstractThe present study examined the antioxidant activity and protective effect of extracts from Asparagus racemosus roots against Lipofectamine-induced apoptosis. Five fractions from a successive extraction process ranging from non-polar to more polar solvents were obtained. The total saponin content as a marker in terms of diosgenin equivalent value of the root extracts was found to be in the range of 240-420μg/mg extract, with higher values for the ethanol and aqueous fractions. The antioxidant activity measured using the DPPH method in terms of mean effective concentration (EC50) of the aqueous fraction was found to be 600 μg/ml as compared to 1.5 μg/ml of ascorbic acid. It is proposed that Asparagus racemosus root extracts effectively inhibit Lipofectamine-induced apoptosis by their protective effect, and may serve as an advantageous alternative option for gene delivery.en_US
dc.rightsMahidol Universityen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleAntioxidant activity and antiapoptotic effect of Asparagus racemosus root extracts in human lung epithelial h460 cellsen_US
Appears in Collections:Scopus 2011-2015

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.