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Title: Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand
Authors: Marcus J. Rijken
Mac Hteld E Boel
Bruce Russell
Mallika Imwong
Mara L. Leimanis
Aung Pyae Phyo
Atis Muehlenbachs
Niklas Lindegardh
Rose McGready
Laurent Rénia
Georges Snounou
Pratap Singhasivanon
François Nosten
Shoklo Malaria Research Unit
Agency for Science, Technology and Research, Singapore
Mahidol University
University of Washington, Seattle
Nuffield Department of Clinical Medicine
Universite Pierre et Marie Curie
Keywords: Immunology and Microbiology;Medicine
Issue Date: 9-May-2011
Citation: Malaria Journal. Vol.10, (2011)
Abstract: Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand. © 2011 Rijken et al; licensee BioMed Central Ltd.
ISSN: 14752875
Appears in Collections:Scopus 2011-2015

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