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dc.contributor.authorUlzii Orshikh Luvsansharaven_US
dc.contributor.authorItaru Hiraien_US
dc.contributor.authorMarie Nikien_US
dc.contributor.authorTadahiro Sasakien_US
dc.contributor.authorKiyoko Makimotoen_US
dc.contributor.authorChalit Komalamisraen_US
dc.contributor.authorWanna Maipanichen_US
dc.contributor.authorTeera Kusolsuken_US
dc.contributor.authorSurapol Sa-Nguankiaten_US
dc.contributor.authorSomchit Pubampenen_US
dc.contributor.authorYoshimasa Yamamotoen_US
dc.contributor.otherOsaka University Faculty of Medicineen_US
dc.contributor.otherKobe University School of Medicineen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-05-03T08:16:43Z-
dc.date.available2018-05-03T08:16:43Z-
dc.date.issued2011-05-01en_US
dc.identifier.citationJournal of Medical Microbiology. Vol.60, No.5 (2011), 619-624en_US
dc.identifier.issn00222615en_US
dc.identifier.other2-s2.0-79955674618en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955674618&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/12055-
dc.description.abstractThe prevalence of and risk factors associated with extended-spectrum β-lactamase (ESBL)-producing micro-organisms have not been well studied in healthy individuals. The aim of this study was to determine this in healthy individuals in Thailand. Stool samples and questionnaires obtained from 445 participants from three provinces in Thailand were analysed. The antimicrobial susceptibility of the isolates was assessed using phenotypic and genotypic methods. PCR analysis was performed to detect and group the bla CTX-M genes. The prevalence of CTX-M-type ESBL-producing Enterobacteriaceae in the three provinces was as follows: 29.3% in Nan (43/147), 29.9% in Nakhon Si Thammarat (43/144) and 50.6% in Kanchanaburi (78/154) (P < 0.001). Of the 445 samples, 33 (7.4%), 1 (0.2%) and 127 (28.5%) isolates belonged to the bla CTX-M gene groups I, III and IV, respectively. Escherichia coli was the predominant member of the Enterobacteriaceae producing CTX-M-type ESBLs (40/43, 39/43 and 70/78 isolates in Nan, Nakhon Si Thammarat and Kanchanaburi, respectively). No statistically significant association was observed between the presence of ESBL-producing bacteria and gender, age, education, food habits or antibiotic usage. However, the provinces that had the highest prevalence of ESBLproducing Enterobacteriaceae also had the highest prevalence of use and purchase of antibiotics without a prescription. Thus, this study revealed that faecal carriage of ESBL-producing Enterobacteriaceae is very high in asymptomatic individuals in Thailand, with some variations among the provinces. This high prevalence may be linked to antibiotic abuse. © 2011 SGM.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955674618&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleAnalysis of risk factors for a high prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae in asymptomatic individuals in rural Thailanden_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1099/jmm.0.026955-0en_US
Appears in Collections:Scopus 2011-2015

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