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Title: Cervical adenoid basal carcinoma associated with invasive squamous cell carcinoma: A report of rare co-existence and review of literature
Authors: Boonlert Viriyapak
Sung Taek Park
Ah Won Lee
Jong Sup Park
Chung Won Lee
Min Jong Song
Soo Young Hur
Mahidol University
The Catholic University of Korea
Keywords: Medicine
Issue Date: 18-Oct-2011
Citation: World Journal of Surgical Oncology. Vol.9, (2011)
Abstract: Cervical adenoid basal carcinoma (ABC) rarely can harbor associated malignancies like adenoid cystic carcinoma or squamous cell carcinoma (SCC), which express markedly different prognosis from a pure ABC, making an appropriate biopsy essential to provide a clear diagnosis and therapeutic plan. We report a 64-year-old asymptomatic lady with an abnormal cervical cytology, who underwent a conization to reveal an ABC with overlying microinvasive SCC. Doubtful resection margins led us to perform radical hysterectomy with lymph node dissection. Subsequent pathological examination showed a true invasive SCC co-existing with ABC, with invasion of the parametrium. Unlike the indolent course of many pure ABC patients, the prognosis of 11 previously reported co-existing invasive SCC with ABC patients appears to depend on the SCC component. Our case reiterates the importance of adequate biopsy with careful interpretation to cover the possibility of a co-existent malignancy. Besides, it presents an argument in favor of radical surgery for the primary treatment of suspicious associated malignancy, and supports adjuvant treatment according to the unfavorable extent of the co-existent invasive carcinoma. © 2011 Viriyapak et al; licensee BioMed Central Ltd.
ISSN: 14777819
Appears in Collections:Scopus 2011-2015

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