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|Title:||Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: Better than we thought|
Nicholas P J Day
Sharon J. Peacock
Department of Clinical Pathology
Nuffield Department of Clinical Medicine
University of Cambridge
|Citation:||Clinical Infectious Diseases. Vol.52, No.8 (2011), 1024-1028|
|Abstract:||We used Bayesian latent-class models to generate receiver operating characteristic curves and to revise the cutoff values for an enzyme-linked immosorbent assay that has been developed previously for melioidosis. The new cutoff was unbiased towards misclassification caused by an imperfect gold standard and resulted in an increase in both sensitivity (from 66.4% to 80.2%) and specificity (82.1% and 95.0%). © 2011 The Author.|
|Appears in Collections:||Scopus 2011-2015|
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