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Title: Measuring herpes zoster, zoster-associated pain, post-herpetic neuralgia-associated loss of quality of life, and healthcare utilization and costs in Thailand
Authors: Kobkul Aunhachoke
Valai Bussaratid
Pornchai Chirachanakul
Boosbun Chua-Intra
Jittima Dhitavat
Kanokporn Jaisathaporn
Jaranit Kaewkungwal
Kowit Kampirapap
Thiravud Khuhaprema
Kulprapat Pairayayutakul
Punnee Pitisuttithum
Jirot Sindhvananda
Yupin Thaipisuttikul
Phramongkutklao College of Medicine
Mahidol University
Thailand Ministry of Public Health
National Cancer Institute Thailand
Institute of Dermatology Thailand
Raj Pracha Samasai Institute
Rajavithi Hospital
Keywords: Medicine
Issue Date: 1-Apr-2011
Citation: International Journal of Dermatology. Vol.50, No.4 (2011), 428-435
Abstract: Objectives This study aimed to measure the herpes zoster-associated burden of illness, healthcare utilization, and costs among Thai patients. Methods This prospective cohort study of 180 patients aged ≥50years and healthy, or ≥20years and immunosuppressed, with zoster rash, was conducted in Bangkok and its environs, Thailand, during 2007-2008. Each patient was followed for sixmonths for zoster-associated rash, pain, quality of life (QoL), and healthcare utilization and costs. Results A total of 180 subjects were enrolled in the study. Their mean±standard deviation (SD) age was 58.9±13.8years. Of the 180 patients enrolled, 138 (76.7%), 34 (18.9%) and eight (4.4%) patients were elderly, HIV-infected, and receiving immunosuppressive agents, respectively; 35 (19.4%) had post-herpetic neuralgia (PHN), and 13 (7.2%) had zoster ophthalmicus. The severity of zoster pain was moderately highly correlated with activities of daily living (ADL), at 0.68≤ρ≤0.76. Most patients required only one or two outpatient visits. The mean±SD total of direct healthcare costs was 3083.4±5047.0 Thai baht or ∼1.1% of annual income per capita. Conclusions Herpes zoster contributes a significant burden of illness to both patients and the wider community. © 2011 The International Society of Dermatology.
ISSN: 13654632
Appears in Collections:Scopus 2011-2015

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