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Title: Performance of Leptospira immunoglobulin M ELISA and rapid immunoglobulin G immunochromatographic assays for the diagnosis of leptospirosis.
Authors: Saowaluk Silpasakorn
Duangdao Waywa
Siriwan Hoontrakul
Chuanpit Suttinont
Kitti Losuwanaluk
Yupin Suputtamongkol
Mahidol University
Keywords: Medicine
Issue Date: 1-Feb-2011
Citation: Journal of the Medical Association of Thailand = Chotmaihet thangphaet. Vol.94 Suppl 1, (2011)
Abstract: Using archived samples, we assessed the diagnostic capacity of two commercially available tests (an ELISA IgM and a rapid immunochromatographic test, ICT) for the detection of Leptospira spp. IgM and IgG antibodies to aid with the diagnosis of acute leptospirosis in febrile patients in Thailand. The sensitivities of the ELISA for the detection of IgM and the rapid immunochromatographic test for the detection of IgG were 60.7% (95% CI, 50.3 to 70.2%), and 83.2% (95% CI 73.9 to 89.6%) respectively. False positive ICT result occurred in one patient with influenza B infection. The positive rates of both assays were high after the first week of onset of fever up to third weeks of illness.
ISSN: 01252208
Appears in Collections:Scopus 2011-2015

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