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Title: Dengue antibody in thai children from maternally transferred antibody to acquired infection
Authors: Krisana Pengsaa
Kriengsak Limkittikul
Sutee Yoksan
Pataporn Wisetsing
Arunee Sabchareon
Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-2011
Citation: Pediatric Infectious Disease Journal. Vol.30, No.10 (2011), 897-900
Abstract: This prospective cohort study examined serotype-specific neutralizing serum antibodies to dengue in 55 maternal-newborn pairs, at 3, 6, 9, 12, 18, and 24 months, and again at 4 to 8 years of age. In all, 95% of the mothers had neutralizing antibody to at least one dengue serotype, and 92.7% of the maternally transferred antibody had disappeared in 12-month-old infants. In all, 31 infants had serologically confirmed dengue infection; 5 symptomatic and 29 inapparent infections were reported. The increasing trend of inapparent infections among the older age group warrants further study of the need for effective dengue vaccination beyond 2 years of age. Copyright © 2011 by Lippincott Williams & Wilkins.
ISSN: 15320987
Appears in Collections:Scopus 2011-2015

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