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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/13385
Title: The Feedback Intervention Trial (FIT) - Improving Hand-Hygiene Compliance in UK Healthcare Workers: A Stepped Wedge Cluster Randomised Controlled Trial
Authors: Christopher Fuller
Susan Michie
Joanne Savage
John McAteer
Sarah Besser
Andre Charlett
Andrew Hayward
Barry D. Cookson
Ben S. Cooper
Georgia Duckworth
Annette Jeanes
Jenny Roberts
Louise Teare
Sheldon Stone
UCL Medical School
UCL
Health Protection Agency
London School of Hygiene & Tropical Medicine
Mid Essex NHS Trust
King's College London
Mahidol University
Keywords: Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology
Issue Date: 23-Oct-2012
Citation: PLoS ONE. Vol.7, No.10 (2012)
Abstract: Introduction: Achieving a sustained improvement in hand-hygiene compliance is the WHO's first global patient safety challenge. There is no RCT evidence showing how to do this. Systematic reviews suggest feedback is most effective and call for long term well designed RCTs, applying behavioural theory to intervention design to optimise effectiveness. Methods: Three year stepped wedge cluster RCT of a feedback intervention testing hypothesis that the intervention was more effective than routine practice in 16 English/Welsh Hospitals (16 Intensive Therapy Units [ITU]; 44 Acute Care of the Elderly [ACE] wards) routinely implementing a national cleanyourhands campaign). Intervention-based on Goal & Control theories. Repeating 4 week cycle (20 mins/week) of observation, feedback and personalised action planning, recorded on forms. Computer-generated stepwise entry of all hospitals to intervention. Hospitals aware only of own allocation. Primary outcome: direct blinded hand hygiene compliance (%). Results: All 16 trusts (60 wards) randomised, 33 wards implemented intervention (11 ITU, 22 ACE). Mixed effects regression analysis (all wards) accounting for confounders, temporal trends, ward type and fidelity to intervention (forms/month used). Intention to Treat Analysis: Estimated odds ratio (OR) for hand hygiene compliance rose post randomisation (1.44; 95% CI 1.18, 1.76;p < 0.001) in ITUs but not ACE wards, equivalent to 7-9% absolute increase in compliance. Per-Protocol Analysis for Implementing Wards: OR for compliance rose for both ACE (1.67 [1.28-2.22]; p < 0.001) & ITUs (2.09 [1.55-2.81];p < 0.001) equating to absolute increases of 10-13% and 13-18% respectively. Fidelity to intervention closely related to compliance on ITUs (OR 1.12 [1.04, 1.20];p = 0.003 per completed form) but not ACE wards. Conclusion: Despite difficulties in implementation, intention-to-treat, per-protocol and fidelity to intervention, analyses showed an intervention coupling feedback to personalised action planning produced moderate but significant sustained improvements in hand-hygiene compliance, in wards implementing a national hand-hygiene campaign. Further implementation studies are needed to maximise the intervention's effect in different settings. Trial Registration: Controlled-Trials.com ISRCTN65246961. © 2012 Fuller et al.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867862589&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/13385
ISSN: 19326203
Appears in Collections:Scopus 2011-2015

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