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Title: Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (review)
Authors: Kiyoshi Kikuchi
Ko Ichi Kawahara
Naoki Miura
Takashi Ito
Yoko Morimoto
Salunya Tancharoen
Nobuyuki Takeshige
Hisaaki Uchikado
Rokudai Sakamoto
Naohisa Miyagi
Chiemi Kikuchi
Narumi Iida
Naoto Shiomi
Terukazu Kuramoto
Masaru Hirohata
Ikuro Maruyama
Motohiro Morioka
Eiichiro Tanaka
Yame Public Hospital
Kurume University School of Medicine
Osaka Institute of Technology
Kagoshima University Faculty of Medicine
Kagoshima University
Mahidol University
Nishida Koutoku Hospital
Kohjin Co., Ltd.
Saiseikai Shiga Hospital
Omuta City General Hospital
Keywords: Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology
Issue Date: 1-Jul-2012
Citation: Experimental and Therapeutic Medicine. Vol.4, No.1 (2012), 3-7
Abstract: Stroke is a major cause of mortality and disability worldwide. During the past three decades, major advances have occurred in secondary prevention, which have demonstrated the broader potential for the prevention of stroke. Risk factors for stroke include previous stroke or transient ischemic attack, hypertension, high blood cholesterol and diabetes. Proven secondary prevention strategies are antiplatelet agents, antihypertensive drugs, statins and glycemic control. In the present review, we evaluated the secondary prevention of stroke in light of clinical studies and discuss new pleiotropic effects beyond the original effects and emerging clinical evidence, with a focus on the effect of optimal oral pharmacotherapy.
ISSN: 17921015
Appears in Collections:Scopus 2011-2015

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