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Title: Quantitative real-time RT-PCR of ITGA7, SVEP1, TNS1, LPHN3, SEMA3G, KLB and MMP13 mRNA expression in breast cancer
Authors: Manas Kotepui
Charin Thawornkuno
Porntip Chavalitshewinkoon-Petmitr
Phaibul Punyarit
Songsak Petmitr
Department of Tropical Nutrition and Food Science
Mahidol University
Army Institute of Pathology
Keywords: Biochemistry, Genetics and Molecular Biology;Medicine
Issue Date: 1-Jan-2012
Citation: Asian Pacific Journal of Cancer Prevention. Vol.13, No.11 (2012), 5879-5882
Abstract: Breast cancer is the leading cause of cancer deaths among women worldwide, including Thailand. In the present study, the differential mRNA expression of SVEP1, LPHN3, KLB, ITGA7, SEMA3G, TNS1 and MMP13 genes was examined in breast cancer using quantitative real-time reverse transcription polymerase chain reaction (QRT-PCR). Among these genes, increased LPHN3 and MMP13 mRNA expression levels correlated with axillary-node metastasis (P=0.02). Multiple logistic regression analysis revealed that LPHN3 and MMP13 mRNA expression is significantly associated with axillary node status in breast cancer (P=0.04).
ISSN: 2476762X
Appears in Collections:Scopus 2011-2015

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