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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/14492
Title: Real-world use of the second-generation cobalt-chromium sirolimus-eluting stents: 12-month results from the prospective multicentre FOCUS registry
Authors: Feng Zhang
Junbo Ge
Juying Qian
Lei Ge
Jun Zhou
Yuejin Yang
Fang Chen
Xiaoling Zhu
Shuzheng Lv
Zhizhong Li
Haichang Wang
Yin Liu
Yawei Xu
Zhanquan Li
Huigen Jin
Weiyi Fang
Xuchen Zhou
Lijun Jing
Yundai Chen
Changyong Zhou
Zhexun Lian
Yi An
Yongjian Yang
Zhixiong Zhong
Zuyi Yuan
Xiaofei Sun
Guotai Sheng
Zhenming Yan
Ren Ke Yi
Jian An
Bin Liu
Zesheng Xu
Xiaoqun Pu
Yongwen Qin
Shuangying Feng
Guosheng Fu
Chunlin Lai
Bo Yu
Tiemin Jiang
Lefeng Wang
Weiming Wang
Jianjun Peng
Hui Li
Wenyue Pang
Biao Xu
Haiming Shi
Meng Wei
Changqian Wang
Ying Zhu
Ningfu Wang
Shaoliang Chen
Qiang Fu
Shian Huang
Keng Wu
Yutian Tong
Zheng Zhang
Ge Zhang
Hesong Zeng
Hong Jiang
Wenwei Liu
Guoying Zhu
Ping Li
Xuekun Zhang
Zhimin Du
Yingfeng Liu
Weimin Li
Ling Liu
Ben He
Wei Gao
Dalin Jia
Jinchuan Yan
Shaorong Liu
Chuanhuan Zhang
Yimin Fang
Zhigang Tao
Jifu Li
He Huang
Xingui Guo
Xinghua Zhang
Tongbao Liu
Lianqun Cui
Jianming Xiao
Lianglong Chen
Jinfa Jiang
Chenzhi Lu
Xueqi Li
Peng Qu
Yan Wang
Honghua Ye
Jingtian Li
Yuqing Hou
Qiutang Zeng
Yuanze Jin
Dongju Jiang
Kanghua Ma
Dadong Zhang
Suwatchai Pornratanarangsi
Muhamad Munawar
Teguh Santoso
Fudan University
Fuwai Cardiovascular Hospital
Beijing Anzhen Hospital
Xijing Hospital
Tianjin Chest Hospital
Shanghai Tenth People's Hospital
People's Hospital of Liaoning Province
Putuo District Central Hospital of Shanghai
Shanghai Chest Hospital
Dalian Medical University
Guangdong General Hospital
Peoples' Liberation Army General Hospital
Qingdao University, School of Medicine
Chengdu Militar General Hospital
Meizhou People's Hospital
Xi'an Jiaotong University, School of Medicine
First People's Hospital of Jining City
Jiangxi Provincial People's Hospital
General Hospital of Fushun Mining Group
Shanxi Provincial Institute of Cardiovascular Disease
Jilin University
Cangzhou Central Hospital
Xiangya Hospital of Zhongnan University
Changhai Hospital
Xingtai Cardiovascular Disease Hospital
Zhejiang University
Shaanxi Provincial People's Hospital
Harbin Medical University
Armed Police Medical College Hospital
Beijing Red Cross Chaoyang Hospital
Peking University
Beijing Shijitan General Hospital
Daqing Oilfield General Hospital
Shengjing Hospital of China Medical University
The Affiliated DrumTower Hospital of Nanjing University Medical School
Shanghai Sixth People's Hospital
Xinhua Hospital
Hangzhou First People's Hospital
Nanjing First Hospital
Xuzhou Centre Hospital
Guangdong Medical College
Weifang Yidu Zhongxin Hospital
Lanzhou University
Kunming Medical College
Huazhong University of Science and Technology
Hubei General Hospital
Xiangfan City Central Hospital
Wuhan Asia Heart Hospital
First People's Hospital of Yulin City
Beijing Luhe Hospital
Sun Yat-Sen University
Zhujiang Hospital
People's Hospital of Guangxi Zhuang Autonomous Region
Renji Hospital
China Medical University Shenyang
Jiangsu University
Yantai Yuhuangding Hospital
Qilu Hospital of Shandong University
Xiangtan Central Hospital
Huadong Hospital
Shandong Provincial Hospital
Fujian Medical University
Tongji University
Tianjin First Central Hospital
Xiamen University
First People's Hospital of Ningbo City
Weifang Medical College
Southern Medical University
Wuhan Union Hospital
The 210th Hospital of PLA
Chongqing Medical University
Shanghai Minhang District Central Hospital
Mahidol University
Bina Waluya Cardiac Hospital
Medistra Hospital
Keywords: Medicine
Issue Date: 1-Dec-2012
Citation: EuroIntervention. Vol.8, No.8 (2012), 896-903
Abstract: Aims: The FOCUS registry is a prospective, multicentre, web-based programme designed to collect clinical outcome data from real-world patients receiving the second-generation cobalt-chromium sirolimus-eluting stent (CoCr-SES). Methods and results: From March 2009 to February 2010, a total of 5,084 patients from 83 centres who were eligible to receive CoCr-SES were enrolled in the FOCUS registry. The primary endpoint was 12-month major adverse cardiac events (MACE, defined as the composite of cardiac death, myocardial infarction [MI] , and target vessel revascularisation [TVR]). One-year data were available for 5,013 (98.6%) of the 5,084 patients enrolled. The primary endpoint occurred in 174 (3.47%) of 5,013 patients, consisting of 43 (0.86%) cardiac deaths, 132 (2.63%) MI, and 46 (0.92%) TVR. According to the Academic Research Consortium definition, definite and probable stent thrombosis (ST) occurred in 0.52% (26/5,013) of patients, including 19 cases of early ST and 7 of late ST. The 12-month MACE rates were 3.73% and 2.60% for extended-use and standard-use patients, respectively (p=0.065). Conclusions: The second-generation CoCr-SES was associated with low rates of 12-month MACE and ST in a broad spectrum of patients, thereby confirming the clinical safety and efficacy of this stent in a real-world setting. © Europa Digital & Publishing 2012. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84872142061&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/14492
ISSN: 19696213
1774024X
Appears in Collections:Scopus 2011-2015

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