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Title: The impact of insecticide-treated school uniforms on dengue infections in school-aged children: Study protocol for a randomised controlled trial in Thailand
Authors: Annelies Wilder-Smith
Peter Byass
Phanthip Olanratmanee
Pongsri Maskhao
Luechai Sringernyuang
James G. Logan
Steve W. Lindsay
Sarah Banks
Duane Gubler
Valérie R. Louis
Yesim Tozan
Pattamaporn Kittayapong
Umea Universitet
Universitat Heidelberg
Mahidol University
Rajabhat Rajanagarindra University
London School of Hygiene & Tropical Medicine
Program in Emerging Infectious Diseases
Boston University School of Public Health
Keywords: Medicine
Issue Date: 15-Nov-2012
Citation: Trials. Vol.13, (2012)
Abstract: Background: There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence.Methods: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons.Discussion: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed.Trial registration: Registration number: NCT01563640. © 2012 Wilder-Smith et al.; licensee BioMed Central Ltd.
ISSN: 17456215
Appears in Collections:Scopus 2011-2015

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