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dc.contributor.authorClaudia Turneren_US
dc.contributor.authorPaul Turneren_US
dc.contributor.authorLinda Poen_US
dc.contributor.authorNaw Maneren_US
dc.contributor.authorAruni De Zoysaen_US
dc.contributor.authorBaharak Afsharen_US
dc.contributor.authorAndroulla Efstratiouen_US
dc.contributor.authorPaul T. Heathen_US
dc.contributor.authorFrançois Nostenen_US
dc.contributor.otherShoklo Malaria Research Uniten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of Oxforden_US
dc.contributor.otherHealth Protection Agencyen_US
dc.contributor.otherSt George's University of Londonen_US
dc.date.accessioned2018-06-11T05:16:09Z-
dc.date.available2018-06-11T05:16:09Z-
dc.date.issued2012-02-08en_US
dc.identifier.citationBMC Infectious Diseases. Vol.12, (2012)en_US
dc.identifier.issn14712334en_US
dc.identifier.other2-s2.0-84856594980en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84856594980&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/14953-
dc.description.abstractBackground: Group B Streptococcus (GBS) is the leading cause of neonatal sepsis in the developed world. Little is known about its epidemiology in the developing world, where the majority of deaths from neonatal infections occur. Maternal carriage of GBS is a prerequisite for the development of early onset GBS neonatal sepsis but there is a paucity of carriage data published from the developing world, in particular South East Asia.Methods: We undertook a cross sectional study over a 13 month period in a remote South East Asian setting on the Thai-Myanmar border. During labour, 549 mothers had a combined vaginal rectal swab taken for GBS culture. All swabs underwent both conventional culture as well as PCR for GBS detection. Cultured GBS isolates were serotyped by latex agglutination, those that were negative or had a weak positive reaction and those that were PCR positive but culture negative were additionally tested using multiplex PCR based on the detection of GBS capsular polysaccharide genes.Results: The GBS carriage rate was 12.0% (95% CI: 9.4-15.0), with 8.6% positive by both culture and PCR and an additional 3.5% positive by PCR alone. Serotypes, Ia, Ib, II, III, IV, V, VI and VII were identified, with II the predominant serotype. All GBS isolates were susceptible to penicillin, ceftriaxone and vancomycin and 43/47 (91.5%) were susceptible to erythromycin and clindamycin.Conclusions: GBS carriage is not uncommon in pregnant women living on the Thai-Myanmar border with a large range of serotypes represented. © 2012 Turner et al; licensee BioMed Central Ltd.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84856594980&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleGroup B streptococcal carriage, serotype distribution and antibiotic susceptibilities in pregnant women at the time of delivery in a refugee population on the Thai-Myanmar borderen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1186/1471-2334-12-34en_US
Appears in Collections:Scopus 2011-2015

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