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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/15400
Title: HIGH RATE OF PLASMODIUM VIVAX RELAPSE FOLLOWING TREATMENT OF FALCIPARUM MALARIA IN THAILAND
Authors: Sornchai Looareesuwan
Nicholas J. White
Danai Bunnag
Sunee Chittamas
Tranakchit Harinasuta
Mahidol University
Nuffield Department of Clinical Medicine
Keywords: Medicine
Issue Date: 7-Nov-1987
Citation: The Lancet. Vol.330, No.8567 (1987), 1052-1055
Abstract: Within two months of treatment for falciparum malaria, Plasmodium vivaxinfections developed in 58 (33%) of 174 patients who had received a quinine or quinidine regimen and in 46 (32%) of 145 patients who had received mefloquine with inpatient follow-up of more than six weeks. The time to vivax relapse was significantly longer after mefloquine treatment (median 47 days, range 30-65) than after quinine or quinidine treatment (21 days, 15-36; p < 0·0001). All patients remained outside areas of malaria transmission. These findings suggest a very high rate of double infection in Thailand with acute suppression of vivax by falciparum malaria, and warrant evaluation of radical therapy with primaquine in certain patients with acute falciparum malaria. © 1987.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0023242493&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/15400
ISSN: 01406736
Appears in Collections:Scopus 1969-1990

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