Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/15679
Title: Clinical importance of antimalarial pharmacokinetics
Authors: J. Karbwang
N. J. White
Mahidol University
Keywords: Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jan-1988
Citation: Asia Pacific Journal of Pharmacology. Vol.3, No.3 (1988), 181-189
Abstract: The efficacy of an antimalarial drug depends on its specific inhibitory or cidal activity on a given species and strain of a malaria parasite. It also depends on pharmacokinetic considerations such as the speed of absorption, concentration of drug in plasma or in infected erythrocytes, distribution in tissues, clearance by metabolism and renal elimination and pharmacodynamic considerations such as toxicity. Recommendations on dosage regimens for antimalaria treatment and prophylaxis should be based on pharmacokinetic and pharmacodynamic studies performed in appropriate populations (i.e. both in volunteers and in children, adults and pregnant women with both uncomplicated and severe malaria).
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0023807742&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/15679
ISSN: 02179687
Appears in Collections:Scopus 1969-1990

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.