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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/15879
Title: Melioidosis: A Major Cause of Community-Acquired Septicemia in Northeastern Thailand
Authors: Wipada Chaowagul
Nicholas J. White
David A.B. Dance
Yupaporn Wattanagoon
Pimjai Naigowit
Timothy M.E. Davis
Sornchai Looareesuwan
Nirun Pitakwatchara
Sappasitthiprasong Hospital
Nuffield Department of Clinical Medicine
Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-1989
Citation: Journal of Infectious Diseases. Vol.159, No.5 (1989), 890-899
Abstract: In a prospective study of all patients with Pseudomonaspseudomallei infections admitted to a large provincial hospital in northeastern Thailand, 63 cases of septicemic melioidosis and 206 patients with other community-acquired septicemias were documented during a 1-y period. Apart from P. pseudomallei, the spectrum of bacteria isolated from blood cultures and the overall mortality (32%) were similar to those previously reported elsewhere. Death from septicemia was associated with failure to develop a leukocytosis or pyrexia over 38°C, azotemia, hypoglycemia, and jaundice. Septicemic melioidosis presented mainly in the rainy season, occurred predominantly in rice farmers or their families, and was significantly associated with preexisting diabetes mellitus or renal failure (P =.03). Blood-borne pneumonia and visceral abscesses were common and the mortality was high (68%; P < .001). The response to appropriate treatment was slow (median fever clearance time 5.5 d) and the median duration of hospital stay was 4 w. Septicemic meloidosis is a major cause of morbidity and mortality in northeast Thailand. © 1989 by The University of Chicago. All Rights Reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0024598313&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/15879
ISSN: 15376613
00221899
Appears in Collections:Scopus 1969-1990

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