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Title: The risk factors in the development of persistent trophoblastic disease following hydatidiform mole.
Authors: S. Tangtrakul
S. Srisupundit
V. Linasmita
S. Bullangpoti
Y. Bhamarapravati
Mahidol University
Keywords: Medicine
Issue Date: 1-Feb-1990
Citation: Journal of the Medical Association of Thailand. Vol.73 Suppl 1, (1990), 33-36
Abstract: Hydatidiform mole (HM) is not uncommon in our country. Its dangerous sequalae is the fatal persistent trophoblastic disease (PTD). The prognostic risk factors for the development of PTD were analyzed in 108 cases of HM treated in Ramathibodi Hospital from 1978 to 1986. Statistical univariate analysis was by calculation of relative risk (RR) and chi-square test. The incidence of PTD was 27.8 per cent. The significant risk factors were the presence of theca-lutein cyst, gestational age of less than 16 weeks, "large for date" uterus, and patients' age of 40 years or more. Their RR were 4.25, 3.11, 3.00 and 2.68 respectively. These findings were comparable with previous reports. The use of prophylactic chemotherapy in patients with these risk factors was suggested.
ISSN: 01252208
Appears in Collections:Scopus 1969-1990

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