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Title: Ocular Findings in Oculodermal Melanocytosis
Authors: Chaiwat Teekhasaenee
Robert Ritch
Uthai Rutnin
Nisit Leelawongs
Mahidol University
New York Eye and Ear Infirmary
Rutnin Hospital
Saint Louise Hospital
Keywords: Medicine
Issue Date: 1-Jan-1990
Citation: Archives of Ophthalmology. Vol.108, No.8 (1990), 1114-1120
Abstract: We examined 194 patients with oculodermal melanocytosis. Dermal involvement alone was present in 67 (34.5%) patients, while 12 (6.2%) had only ocular involvement. The remaining 115 (59.3%) patients had both ocular and dermal pigmentation. Dermal hyperpigmentation in the combined distribution of the ophthalmic and maxillary divisions of the trigeminal nerve and hyperpigmentation of the nasal or buccal mucosa were closely associated with ocular involvement. Ocular hyperpigmentation most commonly involved the episclera. Associated ocular findings included elevated intraocular pressure with or without glaucoma (10.3%), uveitis (2.6%), cataract (1%), asymmetric cupping of the optic nerve head unassociated with glaucoma (9.8%), and orbital melanoma (0.5%). The most serious complication of oculodermal melanocytosis is malignant transformation, while glaucoma appears to be the more common one. Patients with oculodermal melanocytosis and ocular hyperpigmentation should be followed up at regular intervals for the development of either of these complications. © 1990, American Medical Association. All rights reserved.
ISSN: 15383601
Appears in Collections:Scopus 1969-1990

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