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|Title:||Antiserum to the gp116 glycoprotein of yellow head virus neutralizes infectivity in primary lymphoid organ cells of Penaeus monodon|
|Keywords:||Agricultural and Biological Sciences|
|Citation:||Diseases of Aquatic Organisms. Vol.63, No.1 (2005), 85-88|
|Abstract:||Yellow head virus (YHV) is an invertebrate nidovirus that has caused mass mortality of cultured Penaeus monodon in Asia. In this study, we investigated whether mouse polyclonal anti-serum raised against the YHV gp116 or gp64 structural glycoproteins could neutralize YHV infectivity as determined using an in vitro quantal assay in primary cultures of lymphoid organ cells. Anti-gp116 antiserum showed virus-neutralizing activity whereas anti-gp64 antiserum failed to inhibit infection. The results suggest that gp116 antiserum blocks binding of virions to cellular receptors to facilitate YHV entry into lymphoid organ cells.|
|Appears in Collections:||Scopus 2001-2005|
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