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Title: Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion for treatment of septicaemic melioidosis
Authors: Cheardchai Soontornpas
Sumarn Saraya
Malyn Chulasiri
Busba Chindavijak
Piroon Mootsikapun
Khon Kaen University
Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Nov-2005
Citation: International Journal of Antimicrobial Agents. Vol.26, No.5 (2005), 403-407
Abstract: Melioidosis is a fatal community-acquired infection endemic in tropical areas. Ten isolates of the causative microorganism were subjected to time-kill study using a range of ceftazidime concentrations. This study demonstrated that a ceftazidime concentration of eight times the minimum inhibitory concentration yielded an optimal bactericidal effect and should be the target concentration administered by continuous infusion. © 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
ISSN: 09248579
Appears in Collections:Scopus 2001-2005

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