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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/16561
Title: Baseline correlation and comparative kinetics of cerebrospinal fluid colony-forming unit counts and antigen titers in cryptococcal meningitis
Authors: Annemarie E. Brouwer
Paprit Teparrukkul
Supraphada Pinpraphaporn
Robert A. Larsen
Wirongrong Chierakul
Sharon Peacock
Nicholas Day
Nicholas J. White
Thomas S. Harrison
Mahidol University
Sappasitthiprasong Hospital
St George's University of London
Nuffield Department of Clinical Medicine
University of Southern California
Radboud University Nijmegen Medical Centre
Keywords: Immunology and Microbiology;Medicine
Issue Date: 15-Aug-2005
Citation: Journal of Infectious Diseases. Vol.192, No.4 (2005), 681-684
Abstract: Cerebrospinal fluid (CSF) cryptococcal colony-forming unit counts and CSF cryptococcal antigen titers serve as alternative measures of organism load in cryptococcal meningitis. For these measures, we correlated baseline values and rates of decline during the first 2 weeks of therapy in 68 human immunodeficiency virus-seropositive patients with cryptococcal meningitis. At baseline, there was a strong correlation between CSF cryptococcal colony-forming unit counts and CSF cryptococcal antigen titers. During the first 2 weeks of therapy, CSF cryptococcal colony-forming unit counts decreased by >5 logs, and CSF cryptococcal antigen titers decreased by 1.5 dilutions. In individual patients, there was no correlation between the rate of decline in CSF cryptococcal colony-forming unit counts and that in CSF cryptococcal antigen titers. © 2005 by the Infectious Diseases Society of America. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23244460544&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/16561
ISSN: 00221899
Appears in Collections:Scopus 2001-2005

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