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Title: Modulation of immune responses during HIV-malaria co-infection in pregnancy
Authors: Renée M. Ned
Julie M. Moore
Sujittra Chaisavaneeyakorn
Venkatachalam Udhayakumar
National Center for Infectious Diseases
The University of Georgia
Atlanta Research and Education Foundation
Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jun-2005
Citation: Trends in Parasitology. Vol.21, No.6 (2005), 284-291
Abstract: Infection with either HIV or malaria during pregnancy often results in adverse outcomes for mother and child. Co-infection further increases the risks of these events, which include maternal anemia and babies with low birth weight. The immunological bases for the increased susceptibility of HIV-infected mothers to malaria and for the effect of co-infection on mother-to-child transmission of HIV are areas of major importance in public health. In this article, we review current data about humoral and cellular responses to HIV-placental-malaria co-infection and present an immunological hypothesis to explain the epidemiological findings.
ISSN: 14714922
Appears in Collections:Scopus 2001-2005

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