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Title: An unusual electrophysiologic finding in acute stage of Leber's hereditary optic neuropathy
Authors: Wanicha L. Chuenkongkaew
Patthanee Samsen
Patcharee Lertrit
Nualanong Thanasombatsakul
Mahidol University
Faculty of Medicine, Siriraj Hospital, Mahidol University
Keywords: Medicine
Issue Date: 21-Nov-2005
Citation: Neuro-Ophthalmology Japan. Vol.22, No.3 (2005), 454-458
Abstract: A 13-year-old boy developed sequential bilateral visual loss with inter-eye delay of 1 year. Mitochondrial DNA mutation at nucleotide position 11778 of Leber's hereditary optic neuropathy (LHON) was detected in the patient who had affected and unaffected maternal relatives. During the acute stage of visual loss in the right eye, the study of flash visual evoked potential was normal whereas pattern reversal visual evoked potential demonstrated prolonged P100 latency without any amplitude reduction which is unusual for LHON.
ISSN: 02897024
Appears in Collections:Scopus 2001-2005

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