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|Title:||Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand|
Nicholas J. White
Nicholas P.J. Day
Australian Army Malaria Institute
Institut Pasteur, Paris
|Keywords:||Medicine;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Antimicrobial Agents and Chemotherapy. Vol.49, No.10 (2005), 4393-4395|
|Abstract:||The dhps sequences of 55 Plasmodium vivax isolates (39 from Thailand and 16 from elsewhere) revealed mutant Pvdhps at codons 383 and/or 553 (A → G) in 33 isolates, all from Thailand. Mutations of P\dhps and P\dhfr were correlated. Multiple mutations were associated with high-grade sulfadoxine-pyrimethamine resistance. Copyright © 2005, American Society for Microbiology. All Rights Reserved.|
|Appears in Collections:||Scopus 2001-2005|
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