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Title: Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis
Authors: Ponganant Nontasut
Bo A. Claesson
Paron Dekumyoy
Wallop Pakdee
Sukvannee Chullawichit
Mahidol University
Sahlgrenska Universitetssjukhuset
The Hospital for Tropical Diseases, Bangkok
Keywords: Medicine
Issue Date: 1-May-2005
Citation: Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.3 (2005), 650-652
Abstract: A comparative study was performed for the treatment of gnathostomiasis patients with ivermectin 0.2 mg/kg for 2 days in 15 patients vs albendazole 400 mg twice daily for 21 days in 14 patients. The ivermectin and albendazole gave cure rates of 100% and 78.5%, respectively, however the difference was not statistically significant between the two drugs (Fisher's exact, p=0.0996). One year after treatment, the patients who had no migratory swellings and a drop in ELISA titers or a negative immunoblot test were considered to be cured. The side effect of ivermectin for two days was dizziness. The side effects of albendazole were nausea, dizziness, and an increased alkaline phosphatase.
ISSN: 01251562
Appears in Collections:Scopus 2001-2005

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