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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/17011
Title: Breast cancer underestimation rate of atypical ductal hyperplasia diagnosed by core-needle biopsy under imaging guidance
Authors: Cholatip Wiratkapun
Bussanee Wibulpholprasert
Panuwat Lertsithichai
Kamolthum Pulpinyo
Sansanee Wongwaisayawan
Mahidol University
Keywords: Medicine
Issue Date: 1-Apr-2005
Citation: Journal of the Medical Association of Thailand. Vol.88, No.4 (2005), 460-466
Abstract: Objective: To evaluate breast cancer underestimation rate of atypical ductal hyperplasia (ADH) diagnosed by core-needle biopsy (CNB) under imaging guidance in Ramathibodi Hospital and to determine the difference between the malignant and benign groups in terms of clinical and imaging characteristics. Material and Method: The pathological records of 1,521 patients who underwent CNB under imaging guidance were reviewed. Thirty-nine patients diagnosed with ADH were enrolled into the present study. Clinical data, imaging features, biopsy technique and result of excisional biopsy as well as follow-up data were retrospectively reviewed. Results: Of 39 ADH cases, eight (20.5%) were found to have malignancy on subsequent excisional biopsy. The majority of these were ductal carcinoma in situ (DCIS) (62.5%). Lesion categorized as category 5 according to BI-RADS (Breast imaging reporting and data system) was the only feature which was statistically different between the benign and malignant groups. No statistically significant difference was found between the benign and malignant groups in terms of age, personal and family history of breast cancer, clinical finding, mammographic lesion type, size of lesion, image-guided technique and percentage of lesion removal. Conclusion: The underestimation rate of ADH in the present study was comparable to other studies. The finding of BI-RADS category 5 in patients with ADH diagnosed from CNB is a strong indication for subsequent excisional biopsy.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23044435747&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/17011
ISSN: 01252208
Appears in Collections:Scopus 2001-2005

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