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|Title:||Topical antiinflammatory activity of two pimarane diterpenes from Kaempferia pulchra|
Thailand Ministry of Science and Technology
University of Dhaka
|Keywords:||Chemistry;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Phytotherapy Research. Vol.10, No.6 (1996), 534-535|
|Abstract:||Two diterpenes, 2α-acetoxysandraracopimaradien-1α-ol (1) and sandaracopimaradien-1α,2α-diol (2) isolated from Kaempferia pulchra Ridl. (Zingiberaceae), have been assayed for topical antiinflammatory activity in the model of 12-O-tetradecanoylphorbol-13-acetate-induced ear oedema in rats. Both substances were found active and the ID50-values were estimated to be 330 and 50 μg/ear, respectively. The ID50-value of the reference drug diclofenac was calculated to 90 μg/ear.|
|Appears in Collections:||Scopus 1991-2000|
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