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Title: Levels of stem cell factor and interleukin-3 in serum in acute Plasmodium falciparum malaria
Authors: H. Burgmann
S. Looareesuwan
E. C. Wiesinger
W. Winter
W. Graninger
Universitat Wien
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine
Issue Date: 1-Jan-1997
Citation: Clinical and Diagnostic Laboratory Immunology. Vol.4, No.2 (1997), 226-228
Abstract: The purpose of the present study was to measure serum concentrations of stem cell factor (SCF) and interleukin-3 (IL-3) in patients with acute Plasmodium falciparum malaria. Serum samples from 15 patients were taken on day of admission and days 7, 14, 21, and 28. Anemia developed in 80% of patients. A transient increase in IL-3 could be observed at the beginning of the disease. It remains controversial whether the measured concentrations of IL-3 and SCF correlate with the grade of anemia. The possibly suppressed IL-3 and SCF production may contribute to the prolonged anemia in P. falciparum malaria, as has been shown for erythropoietin.
ISSN: 1071412X
Appears in Collections:Scopus 1991-2000

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