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|Title:||Levels of stem cell factor and interleukin-3 in serum in acute Plasmodium falciparum malaria|
E. C. Wiesinger
|Keywords:||Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine|
|Citation:||Clinical and Diagnostic Laboratory Immunology. Vol.4, No.2 (1997), 226-228|
|Abstract:||The purpose of the present study was to measure serum concentrations of stem cell factor (SCF) and interleukin-3 (IL-3) in patients with acute Plasmodium falciparum malaria. Serum samples from 15 patients were taken on day of admission and days 7, 14, 21, and 28. Anemia developed in 80% of patients. A transient increase in IL-3 could be observed at the beginning of the disease. It remains controversial whether the measured concentrations of IL-3 and SCF correlate with the grade of anemia. The possibly suppressed IL-3 and SCF production may contribute to the prolonged anemia in P. falciparum malaria, as has been shown for erythropoietin.|
|Appears in Collections:||Scopus 1991-2000|
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