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|Title:||Complete remission of refractory gestational trophoblastic disease with brain metastases treated with multicycle ifosfamide, carboplatin, and etoposide (ICE) and stem cell rescue|
|Authors:||Koen Van Besien|
Andrzej P. Kudelka
Creighton L. Edwards
John J. Kavanagh
University of Texas MD Anderson Cancer Center
|Citation:||Gynecologic Oncology. Vol.65, No.2 (1997), 366-369|
|Abstract:||Patients with chemotherapy-refractory gestational trophoblastic disease and brain metastasis are considered to have a very poor prognosis. We present the case of a patient who had failed several chemotherapeutic regimens. Despite transient responses to chemotherapy, she had not achieved a complete remission in 3 years, and had developed systemic disease and recurrent brain metastasis. She was treated with four cycles of high-dose ifosfamide, carboplatin, and etoposide with blood progenitor cell support. She tolerated this regimen well and has obtained a complete remission that is ongoing for 12 months.|
|Appears in Collections:||Scopus 1991-2000|
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