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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/18384
Title: Seroprevalence of scrub typhus infection in patients with pyrexia at some malaria clinics in three western provinces of Thailand
Authors: Charnchudhi Chanyasanha
Khanittha Kaeburong
Mongkol Chenchittikul
Dusit Sujirarat
Mahidol University
Thailand Health Systems Research Institute
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jun-1998
Citation: Asian Pacific Journal of Allergy and Immunology. Vol.16, No.2-3 (1998), 119-125
Abstract: In Thailand, the epidemiological data on scrub typhus infection represents only 'the tip of an iceberg' especially in malaria clinics where patients come to seek attention because of other febrile illnesses that may have initial clinical signs that are indistinguishable from malaria. The objectives of this study were to determine the prevalence of antibody titers to Orientia tsutsugamushi, and its various strains, among patients at some malaria clinics in three western provinces of Thailand. The sample was represented by 200 patients from 6 malaria clinics in Ratchaburi, Petchaburi and Kanchanaburi provinces between June and November, 1994. Blood specimens were collected with their consent, Immunofluorescent antibody assays (IFA) were used for measuring IgM and IgG antibody titers for scrub typhus infection. The results showed that the prevalence rate for scrub typhus infection (IgM and/or IgG titer ≥ 50) was 59.50% (119 cases). The immunofluorescent antibody response to various strains of O. tsutsugamushi showed that co-infections with the Karp, the Gilliam and the Kato strains were the most common (found in 68.10% of cases). Geometric mean antibody titers (GMT) were highest for the Karp strain, followed by the Gilliam then Kato strains. In conclusion, this study indicates that the prevalence rate of scrub typhus is not rare in these areas.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0032435679&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/18384
ISSN: 0125877X
Appears in Collections:Scopus 1991-2000

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