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dc.contributor.authorSuradej Hongengen_US
dc.contributor.authorSamart Pakakasamaen_US
dc.contributor.authorAmpaiwan Chuansumriten_US
dc.contributor.authorBusaba Rerkamnuaychokeen_US
dc.contributor.authorPrawat Nitiyanunten_US
dc.contributor.authorUmaporn Suthutvoravuten_US
dc.contributor.authorArtit Ungkanonten_US
dc.contributor.authorPhongjan Hathiraten_US
dc.contributor.otherMahidol Universityen_US
dc.identifier.citationAsian Pacific Journal of Allergy and Immunology. Vol.16, No.4 (1998), 193-198en_US
dc.description.abstractWe described the successful allogeneic matched sibling bone marrow transplantation (BMT) in a 5-year-old Thai boy in whom osteopetrosis was diagnosed on the basis of anemia, thrombocytopenia, leukoerythroblastosis, sclerotic bone, hepatosplenomegaly, and visual deficit from an encroachment of cranial nerve foramina. The preparative regimen included 4 days of busulfan 4mg/kg/day, and 4 days of cyclophosphamide 50 mg/kg/day. Complete hematopoietic engraftment and no evidence of graft versus host disease were shown after BMT. Complete hematologic findings were corrected. His hematopoietic chimerism was changed to that of his donor. Post BMT, he has no hepatosplenomegaly. His bone radiographic findings revealed normal after BMT. Bone marrow biopsy showed normalized bone and bone marrow matrix. However, his vision remained impaired. We believe that this is the first case of successful bone marrow transplantation in an osteopetrosis patient in Thailand.en_US
dc.rightsMahidol Universityen_US
dc.titleAllogeneic bone marrow transplantation in an osteopetrosis patient: First report in Thailanden_US
Appears in Collections:Scopus 1991-2000

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