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Title: In Vitro Activity and Clinical Evaluation of Cefixime in Urinary Tract Infection
Authors: Korntong Asvanich
Vichai Fugpholngam
Somboon Srimuang
Deja Tanphaichitra
Mahidol University
Keywords: Medicine
Issue Date: 1-Apr-1998
Citation: Journal of the Medical Association of Thailand. Vol.81, No.4 (1998), 300-303
Abstract: Thirty-five women with uncomplicated acute lower urinary tract infections proven by significant pre-treatment bacteriuria (≥ 105CFU/ml) were treated with an oral dose of 100 mg cefixime twice a day for seven days. Thirty five patients included in this study were checked for response to treatment on the last day of therapy, 7-14 days and 4 weeks post therapy. The clinical response and bacterial eradication rate for cefixime were 91.4 per cent (32/35). The infecting organisms, E. coli and Proteus mirabilis, were inhibited at MIC90= 0.5 and ≤ 0.03 μg/ml, and MBC = 1 and 0.06 μg/ml respectively. No adverse events were found in this study.
ISSN: 01252208
Appears in Collections:Scopus 1991-2000

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