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dc.contributor.authorPenchom Peungvichaen_US
dc.contributor.authorSuwan S. Thirawarapanen_US
dc.contributor.authorHiroshi Watanabeen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of Toyamaen_US
dc.identifier.citationJapanese Journal of Pharmacology. Vol.78, No.3 (1998), 395-398en_US
dc.description.abstractWe studied the hypoglycemic effect of 4-hydroxybenzoic acid, a constituent of the root of Pandanus odorus Ridl. (Pandanaceae, Thai name: Toei-hom), in streptozotocin-diabetic rats. Oral administration of 4-hydroxybenzoic acid caused a decrease in plasma glucose levels dose-dependently in the diabetic rat. The constituent did not affect serum insulin level and liver glycogen content in the diabetic model, but increased glucose consumption in normal and diabetic rat diaphragms. These results suggest that 4-hydroxybenzoic acid produces a hypoglycemic effect mediated by an increase in the peripheral glucose consumption.en_US
dc.rightsMahidol Universityen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titlePossible mechanism of hypoglycemic effect of 4-hydroxybenzoic acid, a constituent of Pandanus odorus rooten_US
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