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|Title:||Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01|
Chulabhorn Research Institute
The Institute of Science and Technology for Research and Development, Mahidol University
|Keywords:||Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology|
|Citation:||Phytochemistry. Vol.69, No.14 (2008), 2621-2626|
|Abstract:||Nodulisporacid A (1) was isolated from a marine-derived fungus Nodulisporium sp. CRIF1, while vermelhotin (5) was obtained from an unidentified fungus CRI247-01 (a member of the Order Pleosporales). Both 1 and 5 occurred as equilibrium E/Z mixtures. Ester derivatives (2 and 3) and vermelhotin (5) showed cytotoxic activity against eleven cancer cell lines. Nodulisporacid A (1) and vermelhotin (5) exhibited moderate antiplasmodial activity. © 2008 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Scopus 2006-2010|
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