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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/18792
Title: Recent discoveries of new hantaviruses widen their range and question their origins
Authors: Heikki Henttonen
Philippe Buchy
Yupin Suputtamongkol
Sathaporn Jittapalapong
Vincent Herbreteau
Juha Laakkonen
Yannick Chaval
Maxime Galan
Gauthier Dobigny
Nathalie Charbonnel
Johan Michaux
Jean François Cosson
Serge Morand
Jean Pierre Hugot
Metla
Institut Pasteur du Cambodge
Mahidol University
Kasetsart University
Universite Paris Nanterre
INRA Montpellier
Institut des Sciences de l'Evolution UMR 5554
Museum National d'Histoire Naturelle
Keywords: Arts and Humanities;Biochemistry, Genetics and Molecular Biology;Neuroscience
Issue Date: 1-Jan-2008
Citation: Annals of the New York Academy of Sciences. Vol.1149, (2008), 84-89
Abstract: Hantaviruses belong to the Bunyaviridae family. While usually hosted by wild mammals, they are potentially pathogenic for humans, and several serologically distinct groups associated with different syndromes have been identified. Yet, investigations have mostly been conducted where human infections by hantaviruses constitute a real and well-identified public health problem, i.e., the holarctic and neotropical areas. Some hantaviruses have also been described from a Suncus murinus in India and a Bandicota indica in Thailand. In addition, recent investigations in Cambodia revealed new Hantavirus types. More recently, two new Hantavirus species were described: Sangassou from a Hylomyscus simus, and Tanganya from a Crocidura theresae, both from Africa (Guinea), thus strongly questioning the current views about geographic range, evolution, and epidemiology of hantaviruses. In such a framework, we have conducted a survey of Hantavirus diversity in Southeast Asia which allows us to isolate the Thailand virus and address questions about the taxonomy of their rodent hosts. Here we present a molecular analysis of representatives of all currently known Hantavirus species, thus allowing the comparison between the newly described ones with a large range sample of rodent hantaviruses. Our results clearly point to the presence of a particular lineage of hantaviruses in Southeast Asia. It also strongly suggests that new viruses, additional mammalian hosts and different related syndromes in humans are likely to be discovered in the near future, particularly in Southeast Asia and in Africa, where Muridae rodents are highly diversified. Furthermore, additional work is also urgently needed to investigate the hantaviruses associated with Crociduridae and Soricidae. © 2008 New York Academy of Sciences.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=57849125619&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/18792
ISSN: 17496632
00778923
Appears in Collections:Scopus 2006-2010

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