Simple jQuery Dropdowns
Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorManeekarn Chinworrungseeen_US
dc.contributor.authorSuthep Wiyakruttaen_US
dc.contributor.authorNongluksna Sriubolmasen_US
dc.contributor.authorPhitaya Chuailuaen_US
dc.contributor.authorApichart Suksamrarnen_US
dc.contributor.otherSrinakharinwirot Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherChulalongkorn Universityen_US
dc.contributor.otherRamkhamhaeng Universityen_US
dc.identifier.citationArchives of Pharmacal Research. Vol.31, No.5 (2008), 611-616en_US
dc.description.abstractBioassay-guided fractionation of the extract of the endophytic fungus KLAR 5 belonging to order Hypocreales, which was isolated from the twig of Knema laurina (Blume) Warb., resulted in the isolation of brefeldin A (1), 8-deoxy-trichothecin (2), trichothecolone (3), 7α-hydroxytrichodermol (4), and 7α-hydroxyscirpene (5). Compound 5 was isolated from natural source for the first time. Compound 1 was very highly active against human epidermoid carcinoma of the mouth, human breast cancer (BC-1), and human small cell lung cancer (NCI-H187) cells whereas compounds 2 and 4 were selectively active against BC-1 and NCI-H187 cells. Compounds 3 and 5 were moderately active against these three cancer cell lines. © 2008 The Pharmaceutical Society of Korea.en_US
dc.rightsMahidol Universityen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleCytotoxic activities of trichothecenes isolated from an endophytic fungus belonging to order hypocrealesen_US
Appears in Collections:Scopus 2006-2010

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.