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Title: Dichapetalin-type triterpenoids and lignans from the aerial parts of Phyllanthus acutissima
Authors: Patoomratana Tuchinda
Jittra Kornsakulkarn
Manat Pohmakotr
Palangpon Kongsaeree
Samran Prabpai
Chalobon Yoosook
Jitra Kasisit
Chanita Napaswad
Samaisukh Sophasan
Vichai Reutrakul
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Apr-2008
Citation: Journal of Natural Products. Vol.71, No.4 (2008), 655-663
Abstract: Chemical investigation of the aerial parts of Phyllanthus acutissima resulted in the isolation of five new dichapetalin-type triterpenoids, acutissimatriterpenes A-E (1-5), and two new lignans, acutissimalignans A (6) and B (7), along with two known lignans and three known ellagic acid derivatives. The structures of 1-7 were determined mainly on the basis of spectroscopic methods. The compounds obtained were evaluated for cytotoxic and anti-HIV-1 activities. © 2008 American Chemical Society and American Society of Pharmacognosy.
ISSN: 01633864
Appears in Collections:Scopus 2006-2010

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