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Title: Prenatal ultrasonographic findings in "trisomy 13"
Authors: Somsri Pitukkijronnakorn
Patama Promsonthi
Panyu Panburana
Rasig Rangsiprakarn
Apichart Chittacharoen
Mahidol University
Keywords: Medicine
Issue Date: 1-Nov-2008
Citation: Journal of the Medical Association of Thailand. Vol.91, No.11 (2008), 1651-1655
Abstract: Objective: To evaluate the accuracy of prenatal ultrasonographic diagnosis in fetuses with trisomy 13. Material Method: The present study consisted of all fetuses diagnosed of trisomy 13 and delivered at Ramathibodi Hospital between 1997 and 2006. Results: There were 15 cases of trisomy 13. Twelve cases (80.0%) were detected by prenatal ultrasonographic examination, and 3 cases (20.0%) were missed. Mean maternal age was 31.4 years old. Sixty-six percent were diagnosed in 2nd trimester (mean 19.4 weeks). The earliest gestational age for detection was 12 weeks 6 days. The most common abnormal ultrasonographic findings were holoprosencephaly (46.7%), and facial defects (40.0%). Conclusion: The accuracy of prenatal sonographic diagnosis in trisomy 13 fetuses was 80%. The most sensitive prenatal ultrasonographic findings in trisomy 13 were holoprosencephaly and facial defects.
ISSN: 01252208
Appears in Collections:Scopus 2006-2010

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