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Title: Prevalence and sequence diversity of a factor required for actin-based motility in natural populations of Burkholderia species
Authors: Chayada Sitthidet
Joanne M. Stevens
Narisara Chantratita
Bart J. Currie
Sharon J. Peacock
Sunee Korbsrisate
Mark P. Stevens
Mahidol University
The Pirbright Institute
Menzies School of Health Research
Keywords: Medicine
Issue Date: 1-Jul-2008
Citation: Journal of Clinical Microbiology. Vol.46, No.7 (2008), 2418-2422
Abstract: Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires BimA. We report a high degree of conservation of bimA in 99 B. pseudomallei isolates from the area of endemicity. A geographically restricted subset of B. pseudomallei isolates harbored a B. mallei-like bimA allele (12.1%), confounding a differential diagnostic test based on amplification of species-specific bimA regions. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
ISSN: 00951137
Appears in Collections:Scopus 2006-2010

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