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Title: A micronutrient-fortified seasoning powder reduces morbidity and improves short-term cognitive function, but has no effect on anthropometric measures in primary school children in northeast Thailand: A randomized controlled trial
Authors: Mari Skar Manger
Joanne E. McKenzie
Pattanee Winichagoon
Andrew Gray
Visith Chavasit
Tippawan Pongcharoen
Sueppong Gowachirapant
Bruce Ryan
Emorn Wasantwisut
Rosalind S. Gibson
Mahidol University
University of Otago
Monash University
University of Guelph
Keywords: Medicine;Nursing
Issue Date: 1-Jun-2008
Citation: American Journal of Clinical Nutrition. Vol.87, No.6 (2008), 1715-1722
Abstract: Background: Reductions in iodine and zinc deficiencies and improvements in hemoglobin were achieved from a micronutrient-fortified seasoning powder consumed in school lunches by children in northeast Thailand. Objective: The objective was to determine whether fortification with 4 micronutrients in a school lunch results in changes in children's growth, morbidity, and cognitive function compared with no fortification. Design: In a randomized controlled trial of 569 children aged 5.5-13.4 y from 10 schools, we compared the efficacy of a seasoning powder fortified with or without 5 mg Fe, 5 mg Zn, 50 μg I, and 270 μg vitamin A per serving consumed with a school lunch 5 d/wk. Here we report on results of the secondary functional outcomes. Results: The groups were comparable concerning compliance and loss to follow-up. The intervention had no statistically significant effect on anthropometric measures over 31 wk, but reduced the incidence of respiratory-related illnesses [rate ratio (RR): 0.83; 95% CI: 0.73, 0.94], symptoms of runny nose (RR: 0.80; 95% CI: 0.70, 0.92), cough (RR: 0.80; 95% CI: 0.66, 0.96), and diarrhea (RR: 0.38; 95% CI: 0.16, 0.90). For the visual recall test, those in the fortified group recalled 0.5 more items (95% CI: 0.1, 0.9) than did the controls. There were no statistically significant differences between groups in the results of the digits forward and backward tests or in school grades at the conclusion of the 2 semesters. Conclusion: The beneficial effects on morbidity and visual recall over a short period, in addition to some biochemical improvements, highlight the potential of this micronutrient-fortified seasoning powder supplied in a school lunch. This trial was registered at clinical as ACTRN12605000341628. © 2008 American Society for Nutrition.
ISSN: 00029165
Appears in Collections:Scopus 2006-2010

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