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Title: Screening for gastric cancer in Asia: current evidence and practice
Authors: Wai K. Leung
Ming shiang Wu
Yasuo Kakugawa
Jae J. Kim
Khay guan Yeoh
Khean Lee Goh
Kai chun Wu
Deng chyang Wu
Jose Sollano
Udom Kachintorn
Takuji Gotoda
Jaw town Lin
Wei cheng You
Enders KW Ng
Joseph JY Sung
Chinese University of Hong Kong
National Taiwan University
National Cancer Center Hospital
SungKyunKwan University, School of Medicine
National University of Singapore
University of Malaya
The Fourth Military Medical University
Kaohsiung Medical University Chung-Ho Memorial Hospital
University of Santo Tomas, Manila
Mahidol University
Peking University
Keywords: Medicine
Issue Date: 1-Mar-2008
Citation: The Lancet Oncology. Vol.9, No.3 (2008), 279-287
Abstract: Gastric cancer is the second most common cause of death from cancer in Asia. Although surgery is the standard treatment for this disease, early detection and treatment is the only way to reduce mortality. This Review summarises the epidemiology of gastric cancer, and the evidence for, and current practices of, screening in Asia. Few Asian countries have implemented a national screening programme for gastric cancer; most have adopted opportunistic screening of high-risk individuals only. Although screening by endoscopy seems to be the most accurate method for detection of gastric cancer, the availability of endoscopic instruments and expertise for mass screening remains questionable-even in developed countries such as Japan. Therefore, barium studies or serum-pepsinogen testing are sometimes used as the initial screening tool in some countries, and patients with abnormal results are screened by endoscopy. Despite the strong link between infection with Helicobacter pylori and gastric cancer, more data are needed to define the role of its eradication in the prevention of gastric cancer in Asia. At present, there is a paucity of quality data from Asia to lend support for screening for gastric cancer. © 2008 Elsevier Ltd. All rights reserved.
ISSN: 14702045
Appears in Collections:Scopus 2006-2010

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